Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | TNF | P01375 | 1/20 | 0.39 |
| ▸ | TACR3 | P29371 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700864 | 1.00 | KMT2A (0.44) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL1460374 | 0.84 | KMT2A (0.55) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL1144523 | 0.84 | KMT2A (0.55) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL16348950 | 0.84 | KMT2A (0.55) | KMT2AMEN1POLBMAPTALDH1A1 | |
| SCHEMBL5700874 | 0.82 | F2 (0.40) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL5700932 | 0.81 | MEN1 (0.60) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL4029006 | 0.81 | TSHR (0.41) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL5700925 | 0.81 | MEN1 (0.60) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL4029008 | 0.81 | TSHR (0.41) | KMT2AMEN1POLBMAPTRAB9A | |
| SCHEMBL6513372 | 0.81 | CYP2D6 (0.42) | KMT2AMEN1POLBMAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113845485-B | Amino acid derivative and preparation method and application thereof | 湖南中医药大学 | 2023-03-14 | — | — | CN | disclosed |
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |