Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.61 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700866 | 1.00 | ITGB1 (0.61) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700770 | 0.94 | ITGB1 (0.68) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700783 | 0.94 | ITGB1 (0.68) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL7425997 | 0.94 | ITGB1 (0.57) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5701090 | 0.92 | ITGB1 (0.55) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700827 | 0.92 | ITGB1 (0.70) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700821 | 0.92 | ITGB1 (0.70) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| Trifluoroacetic Acid SCHEMBL5701088 | 0.90 | ITGB1 (0.62) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL7647341 | 0.90 | ITGB1 (0.53) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700909 | 0.88 | ITGB1 (0.64) | ITGB1ITGA4ITGB7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1027328-B1 | SUBSTITUTED ANILIDES | AVENTIS PHARMA LTD (GB) | 2006-08-23 | — | — | EP | disclosed |
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |