Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 12/20 | 0.53 |
| ▸ | ITGA4 | P13612 | 12/20 | 0.53 |
| ▸ | ITGB7 | P26010 | 1/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5700873 | 0.90 | ITGB1 (0.61) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700866 | 0.90 | ITGB1 (0.61) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL7425997 | 0.89 | ITGB1 (0.57) | ITGB1ITGA4ITGB7P2RX7MEN1 | |
| SCHEMBL5700770 | 0.87 | ITGB1 (0.68) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700783 | 0.87 | ITGB1 (0.68) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5701090 | 0.86 | ITGB1 (0.55) | ITGB1ITGA4ITGB7P2RX7MEN1 | |
| Trifluoroacetic Acid SCHEMBL5701088 | 0.85 | ITGB1 (0.62) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700821 | 0.82 | ITGB1 (0.70) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700827 | 0.82 | ITGB1 (0.70) | ITGB1ITGA4ITGB7MEN1KMT2A | |
| SCHEMBL5700782 | 0.81 | ITGB1 (0.65) | ITGB1ITGA4ITGB7MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6479519-B1 | INHIBITORS OF CELL ADHESION; TREATMENT OF ASTHMA OR INFLAMMATORY BOWEL DISEASE | AVENTIS PHARMA LIMITED (GB) | 2002-11-12 | — | — | US | disclosed |