Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.44 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CASP3 | P42574 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.42 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29503056 | 1.00 | MAPT (0.54) | MAPTTDP1ALDH1A1L3MBTL1PKM | |
| SCHEMBL29503038 | 0.84 | NPC1 (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL8502908 | 0.84 | NPC1 (0.50) | MAPTTDP1ALDH1A1MEN1KMT2A | |
| SCHEMBL28102498 | 0.84 | MAPT (0.49) | MAPTTDP1ALDH1A1L3MBTL1PKM | |
| SCHEMBL6932185 | 0.83 | MAPT (0.51) | MAPTTDP1ALDH1A1L3MBTL1PKM | |
| SCHEMBL7469868 | 0.81 | MAPT (0.58) | MAPTTDP1ALDH1A1L3MBTL1PKM | |
| SCHEMBL102827 | 0.81 | MAPT (0.72) | MAPTTDP1ALDH1A1L3MBTL1PKM | |
| Water SCHEMBL9749470 | 0.79 | MAPT (0.70) | MAPTTDP1ALDH1A1L3MBTL1PKM | |
| Hydrochloric Acid SCHEMBL5061862 | 0.79 | MAPT (0.70) | MAPTTDP1ALDH1A1L3MBTL1PKM | |
| SCHEMBL27341170 | 0.79 | MAPT (0.70) | MAPTTDP1ALDH1A1L3MBTL1PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109651253-B | Phenylpropanoid ester derivative and application thereof as neuroprotective medicament | 上海医药工业研究院 | 2022-03-25 | — | — | CN | disclosed |
| CN-109651253-A | Cinnamic acid ester derivant and its application as nerve protection medicine | 上海医药工业研究院 | 2019-04-19 | — | — | CN | disclosed |
| EP-1351911-B1 | MATERIALS AND METHODS FOR SYNTHESIZING STILBENES | CANCER RES VENTURES LTD (GB) | 2006-07-26 | — | — | EP | disclosed |