Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.47 |
| ▸ | TUBB1 | Q9H4B7 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | CASP3 | P42574 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701110 | 0.84 | MAPT (0.54) | MAPTTDP1PDE4DTUBB1MEN1 | |
| SCHEMBL29503056 | 0.84 | MAPT (0.54) | MAPTTDP1PDE4DTUBB1MEN1 | |
| SCHEMBL660605 | 0.82 | MAPT (0.55) | MAPTTDP1PDE4DTUBB1MEN1 | |
| Hydrochloric Acid SCHEMBL28473659 | 0.80 | MAPT (0.53) | MAPTTDP1PDE4DTUBB1MEN1 | |
| SCHEMBL28052357 | 0.79 | MAPT (0.51) | MAPTTDP1PDE4DTUBB1MEN1 | |
| SCHEMBL4638173 | 0.78 | MAPT (0.55) | MAPTTDP1PDE4DTUBB1MEN1 | |
| SCHEMBL9726919 | 0.77 | MAPT (0.58) | MAPTTDP1PDE4DTUBB1MEN1 | |
| SCHEMBL17874171 | 0.77 | ALDH1A1 (0.39) | MAPTTDP1PDE4DTUBB1MEN1 | |
| SCHEMBL17874169 | 0.77 | ALDH1A1 (0.39) | MAPTTDP1PDE4DMEN1KMT2A | |
| SCHEMBL4913002 | 0.76 | MAPT (0.56) | MAPTTDP1PDE4DTUBB1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106008480-A | Quinazoline compound containing cinnamamide structure and preparation method and application thereof | 江西科技师范大学 | 2016-10-12 | — | — | CN | disclosed |