Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oleic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP3 | P05413 | 9/20 | 0.83 |
| ▸ | TERT | O14746 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.58 |
| ▸ | BLM | P54132 | 2/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | FABP4 | P15090 | 2/20 | 0.58 |
| ▸ | GMNN | O75496 | 1/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | APEX1 | P27695 | 1/20 | 0.58 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.58 |
| ▸ | RECQL | P46063 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.58 |
| ▸ | MMP2 | P08253 | 1/20 | 0.58 |
| ▸ | FAAH | O00519 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oleic Acid SCHEMBL7686918 | 0.97 | FABP3 (0.83) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL15533450 | 0.97 | FABP3 (0.86) | FABP3TERTMAPTBLMHSD17B10 | |
| Erucic Acid SCHEMBL30876194 | 0.93 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Palmitoleic Acid SCHEMBL2408219 | 0.93 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Nervonic Acid SCHEMBL31621477 | 0.93 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL5979254 | 0.93 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL35217 | 0.93 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL35214 | 0.93 | FABP3 (0.96) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL1203365 | 0.91 | FABP3 (0.92) | FABP3TERTMAPTBLMHSD17B10 | |
| Oleic Acid SCHEMBL27565498 | 0.91 | FABP3 (0.92) | FABP3TERTMAPTBLMHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1393733-B1 | Use of flavonoid-derivatives for the treatment of atopic eczema | MERCK PATENT GMBH (DE) | 2006-08-23 | — | — | EP | disclosed |
| US-20040053860-A1 | Flavonoid derivatives for the treatment of eczema | MERCK PATENT GMBH (DE) | 2004-03-18 | — | — | US | disclosed |
| EP-1393733-A1 | Flavonoid-derivate for the treatment of eczema | MERCK PATENT GmbH (DE) | 2004-03-03 | — | — | EP | disclosed |
| EP-0681468-B1 | SURFACTANT MIXTURES | HENKEL KGAA (DE) | 1997-03-19 | — | — | EP | disclosed |
| EP-0592475-B1 | AQUEOUS SURFACTANT PREPARATIONS | HENKEL KGAA (DE) | 1995-12-13 | — | — | EP | disclosed |
| WO-1994016678-A1 | SURFACTANT MIXTURES | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1994-08-04 | — | — | WO | disclosed |
| WO-1993000417-A2 | AQUEOUS SURFACTANT PREPARATIONS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1993-01-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040053860-A1 | Flavonoid derivatives for the treatment of eczema | TSLP, CYP51A1, TYR | FABP3 3542/4885TERT 1630/4885MAPT 2677/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.