SCHEMBL570139

SCHEMBL570139

O=C1CCCCC(=S)N1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174687 0.94
SCHEMBL407973 0.82
SCHEMBL6449182 0.78
SCHEMBL1335950 0.78
SCHEMBL23028960 0.76 CRBN (0.80)
SCHEMBL8801853 0.76 CRBN (0.80)
SCHEMBL5909153 0.76 CRBN (0.80)
SCHEMBL6049487 0.76 CRBN (0.80)
SCHEMBL7888543 0.76 CRBN (0.80)
SCHEMBL9716416 0.76 CRBN (0.80)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 96 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120196905-A1 SYNTHETIC COMPOUNDS AND METHODS TO DECREASE NICOTINE SELF-ADMINISTRATION HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2012-08-02 US claimed
WO-2012019093-A1 SYNTHETIC COMPOUNDS AND METHODS TO DECREASE NICOTINE SELF-ADMINISTRATION HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2012-02-09 WO claimed
US-20080188527-A1 Synthetic Compounds and Derivatives as Modulators of Smoking or Nicotine Ingestion and Lung Cancer HUMAN BIOMOLECULAR RESEARCH INSTITUTE 2008-08-07 US claimed
WO-2005066162-A1 SYNTHETIC COMPOUNDS AND DERIVATIVES AS MODULATORS OF SMOKING OR NICOTINE INGESTION AND LUNG CANCER HUMAN BIOMOLECULAR RESEARCH INSTITUTE (US) 2005-07-21 WO claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0554436-B1 GABA RECEPTOR MODULATORS EURO CELTIQUE SA (LU) 2000-07-05 EP claimed
US-5591733-A TREATMENT OF ANXIETY, STRESS, INSOMNIA, SEIZURES, STEROIDS, ACTIVE AT GAMMA-AMINOBUTYRIC ACID RECEPTORS UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1997-01-07 US claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0554436-A4 1994-01-12 EP claimed
EP-0554436-A1 GABA RECEPTOR MODULATORS COCENSYS, INC. (US) 1993-08-11 EP claimed
US-5232917-A Tranquillizers; antianxiolytic agents; sedatives; antidepressants; anticonvulsants; neurotransmitters UNIVERSITY OF SOUTHERN CALIFORNIA (US) 1993-08-03 US claimed
WO-1993003732-A1 GABA RECEPTOR MODULATORS COCENSYS, INC. (US) 1993-03-04 WO claimed
US-4358529-A BINDER, A HEXAARYLBIIMIDAZOLE, A DIHYDROPYRIDINE, AND AN IMIDOTHIOESTER OR A TAUTOMER; NONSILVER PHOTOGRAPHY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-11-09 US claimed
US-4346162-A THIO COMPOUNDS IN NONSILVER PHOTGRAPHY E. I. DU PONT DE NEMOURS AND COMPANY (US) 1982-08-24 US claimed
JP-56093881-A None JP disclosed
JP-S5693881-A RUST PREVENTION OF ZINC COATED STEEL MATERIAL NIPPON STEEL CORP 1981-07-29 JP disclosed