Sugi Predict

Sugi Predict / Compounds / SCHEMBL6049487

SCHEMBL6049487

SCHEMBL6049487

O=C1CCCCCCCCCCC(=O)N1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CRBN Q96SW2 6/20 0.80
▸ FKBP5 Q13451 1/20 0.50
▸ ALDH1A1 P00352 3/20 0.47
▸ TRIM24 O15164 2/20 0.47
▸ TRIM33 Q9UPN9 2/20 0.47
▸ OR51E2 Q9H255 1/20 0.45
▸ MAPT P10636 3/20 0.41
▸ MEN1 O00255 2/20 0.40
▸ KMT2A Q03164 2/20 0.40
▸ RAB9A P51151 2/20 0.40
▸ CYP2C19 P33261 2/20 0.40
▸ TSHR P16473 1/20 0.40
▸ HPGD P15428 2/20 0.37
▸ HTT P42858 1/20 0.37
▸ ALOX15 P16050 1/20 0.34
▸ ALOX12 P18054 1/20 0.34
▸ BLM P54132 1/20 0.34
▸ HSD17B10 Q99714 1/20 0.34
▸ MAPK1 P28482 1/20 0.34
▸ NPSR1 Q6W5P4 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2912717 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL8567419 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL18301008 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL9716416 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL19350697 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL23028960 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL8801853 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL5909153 1.00 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33
SCHEMBL1335950 0.96 — —
SCHEMBL7888543 0.93 CRBN (0.80) CRBNFKBP5ALDH1A1TRIM24TRIM33

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117337196-A Pegylated antibody hydroxyl-containing drug conjugates 深圳康源久远生物技术有限公司 2024-01-02 — — CN claimed
CN-119997951-A Method for preventing, alleviating and/or treating PTGS 2-induced skin disorders and related dysfunctions 西姆莱斯股份公司 2025-05-13 — — CN disclosed
CN-119661712-A Antibodies that specifically bind TNFR2 and uses thereof 百泰生物药业有限公司 2025-03-21 — — CN disclosed
CN-119630427-A Anti-FGFR 3 antibody conjugates and medical uses thereof 启德医药科技（苏州）有限公司 2025-03-14 — — CN disclosed
CN-119462943-A Antibodies, linkers, supports, conjugates and uses thereof 启德医药科技（苏州）有限公司 2025-02-18 — — CN disclosed
CN-111886256-B Anti-MICA and/or MICB antibodies and uses thereof 百时美施贵宝公司 2025-01-10 — — CN disclosed
CN-118251241-B Antibodies, linkers, supports, conjugates and uses thereof 启德医药科技（苏州）有限公司 2024-12-13 — — CN disclosed
CN-118574618-A Drug conjugates and methods of making and using the same 艾德森特克斯治疗股份有限公司 2024-08-30 — — CN disclosed
CN-118251241-A Antibodies, linkers, supports, conjugates and uses thereof 启德医药科技（苏州）有限公司 2024-06-25 — — CN disclosed
CN-117486799-A Isomerization process of photocatalytic 1,1' -dicyclohexylamine peroxide 浙江新和成尼龙材料有限公司 2024-02-02 — — CN disclosed
CN-114025844-B Protein tyrosine phosphatase inhibitors and methods of use thereof 卡里科生命科学有限责任公司 2022-07-26 — — CN disclosed
CN-114728972-A Crystalline forms of a C-C chemokine receptor type 4 antagonist and uses thereof 拉普特医疗公司 2022-07-08 — — CN disclosed
CN-114514230-A METTL16 inhibitors and uses thereof 希望之城 2022-05-17 — — CN disclosed
CN-114206848-A Substituted cycloalkyl compounds as modulators of integrated stress pathways 卡里科生命科学有限责任公司 2022-03-18 — — CN disclosed
CN-114025844-A Protein tyrosine phosphatase inhibitors and methods of use thereof 卡里科生命科学有限责任公司 2022-02-08 — — CN disclosed
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2019-10-08 — — US disclosed
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF XIAMEN SINOPEG BIOTECH CO., LTD. (CN) 2018-08-02 — — US disclosed
US-20170260149-A1 A Process for Preparing Olodaterol and Intermediates Thereof REDDY, G. Pratap (IN) 2017-09-14 — — US disclosed
JP-2006008668-A METHOD FOR PRODUCING DECANE-1,10-DICARBOXYLIC IMIDE UBE IND LTD 2006-01-12 — — JP disclosed
WO-2005115988-A1 METHOD FOR PRODUCING DECANE-1,10-DICARBOXYLIC IMIDE UBE INDUSTRIES, LTD. (JP) 2005-12-08 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10434182-B2 Eight-arm polyethylene glycol derivative, production method therefor, and modified bio-related substance thereof MRPL38, ALG8, MRPS18A CRBN 2259/4885FKBP5 3631/4885ALDH1A1 1103/4885
US-20180214561-A1 EIGHT-ARM POLYETHYLENE GLYCOL DERIVATIVE, PRODUCTION METHOD THEREFOR, AND MODIFIEDBIO-RELATEDSUBSTANCETHEREOF MRPL38, CXCL8, ALG8 CRBN 1809/4885FKBP5 3248/4885ALDH1A1 1061/4885
US-20170260149-A1 A Process for Preparing Olodaterol and Intermediates Thereof CYP4A11, CYP11B1, CYP11B2 CRBN 4290/4885FKBP5 4071/4885ALDH1A1 316/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.