SCHEMBL5701455

SCHEMBL5701455

CC(C)=C[SiH2]O[Si](CCC1CC2C=CC1C2)(O[SiH2]C=C(C)C)O[SiH2]C=C(C)C

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.33
KDM4E B2RXH2 1/20 0.33
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701866 0.88 ALDH1A1 (0.32) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL5335697 0.76 KDM4E (0.36) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL16335885 0.75 KDM4E (0.40) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL115037 0.75 KDM4E (0.40) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL10520924 0.74 KDM4E (0.41) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL5701673 0.73 KDM4E (0.33) ALDH1A1KDM4E
SCHEMBL5701637 0.73
SCHEMBL200331 0.72 KDM4E (0.41) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL992101 0.72 KDM4E (0.38) ALDH1A1KDM4EMEN1KMT2A
SCHEMBL5701611 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP claimed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US claimed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US claimed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP claimed
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed