SCHEMBL5701476

SCHEMBL5701476

CC[Si](CC)(CC)O[Si](CCC1CC2C=CC1C2)(O[Si](CC)(CC)CC)O[Si](CC)(CC)CC

nearest known ligand 0.40

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.40
KDM4E B2RXH2 3/20 0.40
MEN1 O00255 2/20 0.31
KMT2A Q03164 2/20 0.31
HTT P42858 1/20 0.31
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL992101 0.84 KDM4E (0.38) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL6063569 0.83 KDM4E (0.41) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL6064427 0.81 ALDH1A1 (0.40) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL200331 0.81 KDM4E (0.41) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL16335885 0.80 KDM4E (0.40) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL115037 0.80 KDM4E (0.40) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL16362627 0.79 KDM4E (0.37) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL29326783 0.78 KDM4E (0.45) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL29325830 0.78 KDM4E (0.45) ALDH1A1KDM4EMEN1KMT2AHTT
SCHEMBL5701449 0.78 ALDH1A1 (0.34) ALDH1A1KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed