SCHEMBL5701563

SCHEMBL5701563

CCCCCCCCCCC(O[SiH3])(O[Si](C)(C)C)O[Si](C)(C)C

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FDPS P14324 9/20 0.35
GGPS1 O95749 7/20 0.35
TSHR P16473 2/20 0.33
THRB P10828 1/20 0.33
SMPD1 P17405 3/20 0.32
LMNA P02545 2/20 0.32
ALDH1A1 P00352 1/20 0.32
HSD17B10 Q99714 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
CES2 O00748 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701552 1.00 FDPS (0.35) FDPSGGPS1TSHRTHRBSMPD1
SCHEMBL5702103 0.85
SCHEMBL5701870 0.82 FDPS (0.34) FDPSGGPS1TSHRTHRBSMPD1
SCHEMBL5702113 0.82 FDPS (0.34) FDPSGGPS1TSHRTHRBSMPD1
SCHEMBL5701526 0.80 TSHR (0.32) FDPSGGPS1TSHRSMPD1
SCHEMBL5701395 0.80 TSHR (0.32) FDPSGGPS1TSHRSMPD1
SCHEMBL5701622 0.79
SCHEMBL25277174 0.76 TSHR (0.38) FDPSGGPS1TSHRTHRBSMPD1
SCHEMBL25274570 0.76 TSHR (0.38) FDPSGGPS1TSHRTHRBSMPD1
SCHEMBL25272519 0.76 TSHR (0.38) FDPSGGPS1TSHRTHRBSMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed