Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701623 | 0.89 | LMNA (0.32) | — | |
| SCHEMBL5701952 | 0.87 | — | — | |
| SCHEMBL5701386 | 0.77 | TSHR (0.31) | TSHRTDP1 | |
| SCHEMBL5701619 | 0.76 | LMNA (0.39) | TSHRALDH1A1 | |
| SCHEMBL5701505 | 0.76 | LMNA (0.39) | TSHRALDH1A1 | |
| SCHEMBL5701696 | 0.76 | — | — | |
| SCHEMBL1257228 | 0.75 | TSHR (0.30) | TSHRTDP1ALDH1A1 | |
| SCHEMBL5245680 | 0.74 | — | — | |
| SCHEMBL1134146 | 0.73 | TSHR (0.35) | TSHRTDP1ALDH1A1 | |
| SCHEMBL22876301 | 0.71 | TSHR (0.33) | TSHRTDP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |