Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 4/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701895 | 0.80 | MAPK1 (0.31) | MAPK1KCNN4 | |
| SCHEMBL5702112 | 0.79 | KCNN4 (0.34) | MAPK1ALDH1A1ALOX15KCNN4CYP2C19 | |
| SCHEMBL7056377 | 0.76 | MAPK1 (0.41) | MAPK1ALDH1A1ALOX15KCNN4TSHR | |
| SCHEMBL3118068 | 0.73 | MAPK1 (0.42) | MAPK1ALDH1A1ALOX15KCNN4TSHR | |
| SCHEMBL4629554 | 0.73 | MAPK1 (0.42) | MAPK1ALDH1A1ALOX15KCNN4TSHR | |
| SCHEMBL4666868 | 0.71 | MAPK1 (0.46) | MAPK1ALDH1A1ALOX15KCNN4CYP2C19 | |
| SCHEMBL14292070 | 0.71 | MAPK1 (0.46) | MAPK1ALDH1A1ALOX15KCNN4CYP2C19 | |
| SCHEMBL10881380 | 0.71 | MAPK1 (0.41) | MAPK1ALDH1A1ALOX15KCNN4TSHR | |
| SCHEMBL474157 | 0.71 | KCNN4 (0.38) | MAPK1ALDH1A1ALOX15KCNN4TAAR1 | |
| SCHEMBL5701655 | 0.71 | MAPK1 (0.37) | MAPK1ALDH1A1ALOX15KCNN4TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |