SCHEMBL5701767

SCHEMBL5701767

CC=CC(=O)OCCCC(O[SiH3])(O[SiH](C)C)O[SiH](C)C

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.38
HCAR2 Q8TDS4 3/20 0.34
MAPT P10636 1/20 0.31
RAB9A P51151 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701983 0.84 TSHR (0.47) ATM
SCHEMBL397025 0.81 ATM (0.39) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL5701408 0.81 TSHR (0.51) ATMHCAR2
SCHEMBL5701783 0.81 ATM (0.36) ATMHCAR2
SCHEMBL4753651 0.80 ATM (0.38) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL845750 0.79 ATM (0.44) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL5701435 0.78 ATM (0.39) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL7568666 0.77 ATM (0.43) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL1225126 0.76 ATM (0.42) ATMHCAR2MAPTRAB9ANPSR1
SCHEMBL5701676 0.76 ATM (0.34) ATMHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed