SCHEMBL5701783

SCHEMBL5701783

CC=CC(=O)OCCCC(CO[SiH3])(O[SiH](C)C)O[SiH](C)C

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ATM Q13315 1/20 0.36
HCAR2 Q8TDS4 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5701403 0.85 TSHR (0.45) ATM
SCHEMBL7638065 0.85 ATM (0.39) ATMHCAR2
SCHEMBL5702090 0.82 ATM (0.37) ATMHCAR2
SCHEMBL5701767 0.81 ATM (0.38) ATMHCAR2
SCHEMBL7593519 0.80 ATM (0.42) ATMHCAR2
SCHEMBL5702133 0.79 ATM (0.37) ATMHCAR2
SCHEMBL8898992 0.79 ATM (0.41) ATMHCAR2
SCHEMBL1224518 0.77 ATM (0.40) ATMHCAR2
SCHEMBL5702059 0.77 ATM (0.33) ATMHCAR2
SCHEMBL1501104 0.76 ATM (0.42) ATMHCAR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1510520-B1 Preparation of branched siloxane SHINETSU CHEMICAL CO (JP) 2006-07-26 EP disclosed
US-6943264-B2 Preparation of branched siloxane SHIN-ETSU CHEMICAL, CO., LTD. (JP) 2005-09-13 US disclosed
US-20050049427-A1 Preparation of branched siloxane SHIN-ETSU CHEMICAL CO., LTD. (JP) 2005-03-03 US disclosed
EP-1510520-A1 Preparation of branched siloxane Shin-Etsu Chemical Co., Ltd. (JP) 2005-03-02 EP disclosed