Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.43 |
| ▸ | ACE | P12821 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GBA1 | P04062 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.36 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.36 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.36 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.36 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | KCNK3 | O14649 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702265 | 1.00 | GBA2 (0.45) | GBA2CYP3A4CYP2D6KCNH2NR1I2 | |
| SCHEMBL3880995 | 0.94 | GBA1 (0.45) | GBA2CYP3A4CYP2D6KCNH2NR1I2 | |
| SCHEMBL7132021 | 0.94 | GBA1 (0.45) | GBA2CYP3A4CYP2D6KCNH2NR1I2 | |
| SCHEMBL7567165 | 0.94 | GBA1 (0.45) | GBA2CYP3A4CYP2D6KCNH2NR1I2 | |
| SCHEMBL28572785 | 0.93 | GBA1 (0.47) | GBA2CYP3A4CYP2D6KCNH2ACE | |
| SCHEMBL2638664 | 0.89 | NR1I2 (0.55) | CYP3A4CYP2D6KCNH2NR1I2ACE | |
| SCHEMBL13974938 | 0.89 | NR1I2 (0.55) | CYP3A4CYP2D6KCNH2NR1I2ACE | |
| SCHEMBL8892725 | 0.89 | NR1I2 (0.55) | CYP3A4CYP2D6KCNH2NR1I2ACE | |
| SCHEMBL5701854 | 0.88 | ACE (0.44) | CYP3A4CYP2D6KCNH2ACESMN1; SMN2 | |
| SCHEMBL12191654 | 0.88 | ACE (0.44) | CYP3A4CYP2D6KCNH2ACESMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |