Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA1 | P04062 | 1/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.41 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.41 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.41 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GBA2 | Q9HCG7 | 2/20 | 0.40 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 5/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GNAI3 | P08754 | 2/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 2/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3880995 | 1.00 | GBA1 (0.45) | GBA1ACES1PR4S1PR1S1PR3 | |
| SCHEMBL7132021 | 1.00 | GBA1 (0.45) | GBA1ACES1PR4S1PR1S1PR3 | |
| SCHEMBL28572785 | 0.98 | GBA1 (0.47) | GBA1ACES1PR4S1PR1S1PR3 | |
| SCHEMBL5702265 | 0.94 | GBA2 (0.45) | GBA1ACES1PR4S1PR1S1PR3 | |
| SCHEMBL5701883 | 0.94 | GBA2 (0.45) | GBA1ACES1PR4S1PR1S1PR3 | |
| SCHEMBL1381895 | 0.89 | NR1I2 (0.50) | GBA1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL1381896 | 0.89 | NR1I2 (0.50) | GBA1S1PR4S1PR1S1PR3S1PR5 | |
| Ammonia Solution, Strong SCHEMBL8225849 | 0.88 | NR1I2 (0.49) | GBA1S1PR4S1PR1S1PR3S1PR5 | |
| SCHEMBL4947692 | 0.88 | SMN1; SMN2 (0.50) | S1PR4S1PR1S1PR3S1PR5KCNH2 | |
| SCHEMBL7114016 | 0.88 | SMN1; SMN2 (0.50) | S1PR4S1PR1S1PR3S1PR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0970049-B1 | PROCESS FOR THE PRODUCTION OF ENANTIOMERICALLY ENRICHED N-ACYLAZETIDINE-2-CARBOXYLIC ACIDS | ASTRAZENECA AB (SE) | 2002-06-05 | — | — | EP | disclosed |
| US-6054594-A | Process for the production of enantiomerically enriched N-acylazetidine-2-carboxylic acids | ASTRA AB (SE) | 2000-04-25 | — | — | US | disclosed |
| EP-0970049-A1 | PROCESS FOR THE PRODUCTION OF ENANTIOMERICALLY ENRICHED $i(N)-ACYLAZETIDINE-2-CARBOXYLIC ACIDS | Astra Aktiebolag (SE) | 2000-01-12 | — | — | EP | disclosed |
| WO-1998002417-A1 | PROCESS FOR THE PRODUCTION OF ENANTIOMERICALLY ENRICHED N-ACYLAZETIDINE-2-CARBOXYLIC ACIDS | ASTRA AKTIEBOLAG (SE) | 1998-01-22 | — | — | WO | disclosed |