Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.32 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701615 | 1.00 | TSHR (0.37) | TSHRLMNAZDHHC20ZDHHC2THRB | |
| SCHEMBL5701405 | 0.91 | LMNA (0.43) | TSHRLMNAZDHHC20ZDHHC2 | |
| SCHEMBL5701531 | 0.91 | LMNA (0.43) | TSHRLMNAZDHHC20ZDHHC2 | |
| SCHEMBL5702128 | 0.89 | TSHR (0.32) | TSHRLMNA | |
| SCHEMBL5702017 | 0.89 | TSHR (0.32) | TSHRLMNA | |
| SCHEMBL5246690 | 0.83 | — | — | |
| SCHEMBL5701406 | 0.81 | TSHR (0.34) | TSHRZDHHC20ZDHHC2FAAH | |
| SCHEMBL5701392 | 0.81 | TSHR (0.34) | TSHRZDHHC20ZDHHC2FAAH | |
| SCHEMBL16438103 | 0.78 | TSHR (0.32) | TSHR | |
| SCHEMBL12245432 | 0.78 | TSHR (0.32) | TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |