Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | NPBWR1 | P48145 | 1/20 | 0.43 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.43 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.43 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.43 |
| ▸ | CCR2 | P41597 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5701943 | 1.00 | S1PR5 (0.46) | S1PR5SIGMAR1GAADRD4MEN1 | |
| SCHEMBL2032294 | 0.90 | CYP1A2 (0.51) | GAANPBWR1MCHR1PDCD1CD274 | |
| SCHEMBL1817183 | 0.90 | CYP1A2 (0.51) | GAANPBWR1MCHR1PDCD1CD274 | |
| SCHEMBL3148407 | 0.90 | CYP1A2 (0.51) | GAANPBWR1MCHR1PDCD1CD274 | |
| SCHEMBL3713849 | 0.89 | NPBWR1 (0.54) | NPBWR1MCHR1PDCD1CD274CCR2 | |
| SCHEMBL3713847 | 0.89 | NPBWR1 (0.54) | NPBWR1MCHR1PDCD1CD274CCR2 | |
| SCHEMBL2771071 | 0.86 | GRM6 (0.54) | S1PR5SIGMAR1MEN1KMT2APDCD1 | |
| SCHEMBL2771075 | 0.86 | GRM6 (0.54) | S1PR5SIGMAR1MEN1KMT2APDCD1 | |
| SCHEMBL2771498 | 0.86 | GRM6 (0.54) | S1PR5SIGMAR1MEN1KMT2APDCD1 | |
| SCHEMBL24976319 | 0.85 | NOTUM (0.43) | S1PR5SIGMAR1PDCD1CD274NOTUM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0974670-B1 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL CO (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-6143554-A | Process for producing optically active n-substituted azetidine-2 carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-11-07 | — | — | US | disclosed |
| EP-0974670-A2 | Process for producing optically active N-substituted azetidine-2-carboxylic acid compound | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-01-26 | — | — | EP | disclosed |