Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5702090 | 0.88 | ATM (0.37) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL5701477 | 0.86 | TSHR (0.46) | ATM | |
| SCHEMBL5702059 | 0.82 | ATM (0.33) | ATMHCAR2 | |
| SCHEMBL7638065 | 0.82 | ATM (0.39) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL5701435 | 0.82 | ATM (0.39) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL5701783 | 0.79 | ATM (0.36) | ATMHCAR2 | |
| SCHEMBL7593519 | 0.78 | ATM (0.42) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL1501104 | 0.77 | ATM (0.42) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL8898992 | 0.76 | ATM (0.41) | ATMHCAR2MAPTRAB9ANPSR1 | |
| SCHEMBL1224518 | 0.75 | ATM (0.40) | ATMHCAR2MAPTRAB9ANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1510520-B1 | Preparation of branched siloxane | SHINETSU CHEMICAL CO (JP) | 2006-07-26 | — | — | EP | disclosed |
| US-6943264-B2 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL, CO., LTD. (JP) | 2005-09-13 | — | — | US | disclosed |
| US-20050049427-A1 | Preparation of branched siloxane | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2005-03-03 | — | — | US | disclosed |
| EP-1510520-A1 | Preparation of branched siloxane | Shin-Etsu Chemical Co., Ltd. (JP) | 2005-03-02 | — | — | EP | disclosed |