Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.75 |
| ▸ | POLB | P06746 | 3/20 | 0.75 |
| ▸ | MAPT | P10636 | 3/20 | 0.75 |
| ▸ | MITF | O75030 | 2/20 | 0.75 |
| ▸ | LMNA | P02545 | 2/20 | 0.75 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.75 |
| ▸ | GAA | P10253 | 2/20 | 0.75 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.75 |
| ▸ | HTT | P42858 | 1/20 | 0.75 |
| ▸ | UBE2N | P61088 | 2/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | GRIN2D | O15399 | 7/20 | 0.57 |
| ▸ | GRIN3B | O60391 | 7/20 | 0.57 |
| ▸ | GRIN1 | Q05586 | 7/20 | 0.57 |
| ▸ | GRIN2A | Q12879 | 7/20 | 0.57 |
| ▸ | GRIN2B | Q13224 | 7/20 | 0.57 |
| ▸ | GRIN2C | Q14957 | 7/20 | 0.57 |
| ▸ | GRIN3A | Q8TCU5 | 7/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22830618 | 0.87 | KMT2A (1.00) | KMT2APOLBMAPTMITFLMNA | |
| Hydrochloric Acid SCHEMBL5703164 | 0.78 | GRIN2D (0.69) | KMT2AMAPTLMNASMN1; SMN2HTT | |
| SCHEMBL5702988 | 0.75 | KMT2A (0.56) | KMT2AMAPTLMNASMN1; SMN2GAA | |
| SCHEMBL5702992 | 0.75 | KMT2A (0.56) | KMT2AMAPTLMNASMN1; SMN2GAA | |
| SCHEMBL4940997 | 0.75 | GAA (0.64) | KMT2APOLBMAPTSMN1; SMN2GAA | |
| SCHEMBL4941002 | 0.75 | GAA (0.64) | KMT2APOLBMAPTSMN1; SMN2GAA | |
| Hydrochloric Acid SCHEMBL5703137 | 0.74 | CCR5 (0.70) | TLR4 | |
| SCHEMBL2608363 | 0.74 | MEN1 (1.00) | KMT2APOLBMAPTGAAMEN1 | |
| SCHEMBL2834159 | 0.73 | MAPT (0.63) | KMT2APOLBMAPTMITFLMNA | |
| SCHEMBL2834157 | 0.73 | MAPT (0.63) | KMT2APOLBMAPTMITFLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1687641-A2 | TREATING NEUROPATHIC PAIN WITH NEUROPEPTIDE FF RECEPTOR 2 AGONISTS | Acadia Pharmaceuticals Inc. (US) | 2006-08-09 | — | — | EP | disclosed |
| WO-2005031000-A2 | TREATING NEUROPATHIC PAIN WITH NEUROPEPTIDE FF RECEPTOR 2 AGONISTS | ACADIA PHARMACEUTICALS INC. (US) | 2005-04-07 | — | — | WO | disclosed |