SCHEMBL5703136

SCHEMBL5703136

CO[Si](CCCSSNC1CCCCC1)(OC)OC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
EPHX2 P34913 3/20 0.31
LMNA P02545 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5703241 0.86 EPHX2 (0.31) EPHX2LMNASMN1; SMN2
SCHEMBL5703371 0.86 EPHX2 (0.33) EPHX2LMNASMN1; SMN2
SCHEMBL3851050 0.85
SCHEMBL4445525 0.72
SCHEMBL5703239 0.72
SCHEMBL56457 0.71 KDM4E (0.42) EPHX2LMNA
SCHEMBL79932 0.71 LMNA (0.39) LMNA
SCHEMBL15360533 0.70 CXCR4 (0.42) EPHX2
Cyclohexylamine SCHEMBL3858342 0.70
SCHEMBL380401 0.67 LMNA (0.36) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7576153-B2 Tire rubber composition comprising a coupling agent having a polythiosulfenamide function MICHELIN RECHERCHE ET TECHNIQUE S.A. (CH) 2009-08-18 US disclosed
EP-1456215-B1 ORGANOSILICON COMPOUNDS, ELASTOMER COMPOSITIONS AND ARTICLES RHODIA CHIMIE SA (FR) 2006-08-09 EP disclosed
EP-1456215-A1 ORGANOSILICON COMPOUNDS, ELASTOMER COMPOSITIONS AND ARTICLES Rhodia Chimie (FR) 2004-09-15 EP disclosed
WO-2003053983-A1 ORGANOSILICON COMPOUNDS, ELASTOMER COMPOSITIONS AND ARTICLES RHODIA CHIMIE (FR) 2003-07-03 WO disclosed