Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.58 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6859736 | 0.84 | CCR1 (0.49) | CCR1CHRM2CCR5 | |
| SCHEMBL3250560 | 0.81 | CCR1 (0.50) | CCR1CHRM2CCR5 | |
| SCHEMBL1276527 | 0.81 | CCR1 (0.87) | CCR1CHRM2CCR5 | |
| SCHEMBL651958 | 0.81 | CCR1 (0.87) | CCR1CHRM2CCR5 | |
| SCHEMBL10288018 | 0.81 | CCR1 (0.87) | CCR1CHRM2CCR5 | |
| SCHEMBL6859353 | 0.79 | CCR1 (0.41) | CCR1CHRM2CCR5 | |
| SCHEMBL6861133 | 0.77 | CCR1 (0.48) | CCR1CHRM2CCR5 | |
| SCHEMBL16312671 | 0.76 | CCR1 (0.83) | CCR1CHRM2CCR5 | |
| SCHEMBL6852936 | 0.76 | CCR1 (0.40) | CCR1CHRM2CCR5 | |
| SCHEMBL10288016 | 0.75 | CCR1 (0.53) | CCR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1688418-A2 | Chemokine receptor antagonists and methods of use thereof | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2006-08-09 | — | — | EP | disclosed |