Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL569891 | 0.83 | MEN1 (0.53) | MAPTHDAC3HDAC1MEN1KMT2A | |
| SCHEMBL570469 | 0.81 | FLT3 (0.56) | RAB9AKDM4ESMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL10182254 | 0.80 | NPC1 (0.48) | RAB9AKDM4ESMN1; SMN2POLBHSD17B10 | |
| SCHEMBL10182311 | 0.78 | HDAC1 (0.54) | MAPTKDM4ENR4A2HDAC3HDAC1 | |
| SCHEMBL10083554 | 0.78 | KMT2A (0.44) | MAPTHDAC3HDAC1POLBHSD17B10 | |
| SCHEMBL570321 | 0.77 | NPC1 (0.45) | MAPTRAB9ASMN1; SMN2HDAC3HDAC1 | |
| SCHEMBL570358 | 0.76 | ABL1 (0.43) | MAPTHDAC3HDAC1POLBKMT2A | |
| SCHEMBL10182509 | 0.76 | MEN1 (0.47) | MAPTMAPK1RAB9AKDM4ESMN1; SMN2 | |
| SCHEMBL570393 | 0.76 | DRD2 (0.47) | MAPTRAB9AKDM4ESMN1; SMN2POLB | |
| SCHEMBL10183283 | 0.75 | HDAC3 (0.52) | MAPTMAPK1KDM4ESMN1; SMN2HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2601208-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | Graffinity Pharmaceuticals GmbH (DE) | 2013-06-12 | — | — | EP | disclosed |
| WO-2012017021-A2 | LIGANDS FOR ANTIBODY AND Fc-FUSION PROTEIN PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2012-02-09 | — | — | WO | disclosed |