Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 13/20 | 0.49 |
| ▸ | PDE4A | P27815 | 12/20 | 0.49 |
| ▸ | PDE4C | Q08493 | 12/20 | 0.49 |
| ▸ | PDE4D | Q08499 | 12/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2976650 | 1.00 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL5704516 | 0.95 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2978829 | 0.95 | PDE4B (0.52) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL5704662 | 0.82 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2980324 | 0.82 | PDE4B (0.48) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2982022 | 0.81 | POLB (0.55) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2980679 | 0.79 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2972153 | 0.79 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2972157 | 0.79 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DTSHR | |
| SCHEMBL2971159 | 0.79 | PDE4B (0.49) | PDE4BPDE4APDE4CPDE4DTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0994100-B1 | 3-ANILINO-2-CYCLOALKENONE DERIVATES | NIKKEN CHEMICALS CO LTD (JP) | 2006-08-30 | — | — | EP | disclosed |
| US-6235736-B1 | ANTIINFLAMMATORY AGENTS | NIKKEN CHEMICALS CO., LTD. (JP) | 2001-05-22 | — | — | US | disclosed |
| EP-0994100-A1 | 3-ANILINO-2-CYCLOALKENONE DERIVATES | Nikken Chemicals Company, Limited (JP) | 2000-04-19 | — | — | EP | disclosed |