SCHEMBL5704649

SCHEMBL5704649

FC(Cl)C(F)(F)OCC(F)(F)F

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
HTT P42858 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14973403 0.80 MEN1 (0.32) MEN1KMT2A
SCHEMBL3363315 0.78 MEN1 (0.32) MEN1KMT2A
SCHEMBL661236 0.78 HTT (0.33) HTT
SCHEMBL8939814 0.77 MEN1 (0.33) MEN1KMT2AHTT
SCHEMBL9522967 0.74
SCHEMBL2003790 0.74
SCHEMBL775067 0.74 HTT (0.31) HTT
SCHEMBL30872015 0.73 MEN1 (0.31) MEN1KMT2A
Methoxyflurane SCHEMBL8680854 0.72
SCHEMBL12298408 0.70 MEN1 (0.33) MEN1KMT2AHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US claimed
EP-1425318-B1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS VERSALIS SPA (IT) 2013-01-16 EP disclosed
EP-1303258-B1 NOVEL AEROSOL FORMULATION CONTAINING A POLAR FLUORINATED MOLECULE ASTRAZENECA AB (SE) 2006-10-11 EP disclosed
US-7081505-B2 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2006-07-25 US disclosed
EP-0771822-B1 Catalytic system for the (co)polymerization of alpha-olefins POLIMERI EUROPA SPA (IT) 2005-04-13 EP disclosed
US-20040198934-A1 Activating organometallic composition for the (co) polymerization of alpha-olefins comprising fluorinated cyclopentadienyl compounds POLIMERI EUROPA S.P.A. (IT) 2004-10-07 US disclosed
EP-1425318-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS Polimeri Europa S.p.A. (IT) 2004-06-09 EP disclosed
US-20030194378-A1 Novel aerosol formulation containing a polar fluorinated molecule ASTRAZENECA AB (SE) 2003-10-16 US disclosed
WO-2003010210-A1 ACTIVATING ORGANOMETALLIC COMPOSITION FOR THE (CO)POLYMERIZATION OF ALPHA-OLEFINS COMPRISING FLUORINATED CYCLOPENTADIENYL COMPOUNDS POLIMERI EUROPA S.P.A. (IT) 2003-02-06 WO disclosed
US-6274529-B1 COORDINATION CATALYST CONTAINS METALLOCENE OF HAFNIUM, TITANIUM, OR ZIRCONIUM, AND HETEROCOMPOUND CONTAINING OXYGEN, NITROGEN, SULFUR, AND/OR PHOSPHORUS ENICHEM S.P.A. (IT) 2001-08-14 US disclosed
US-5744678-A NICKEL COMPOUND, ORGANOPHOSPHORUS COMPOUND, ORGANOALUMINUM COMPOUND, CARBON-HALOGEN COMPOUNDS; CATALYST SELECTIVITY NIPPON OIL CO., LTD. (JP) 1998-04-28 US disclosed
EP-0771822-A1 Catalytic system for the (co)polymerization of alpha-olefins ENICHEM S.p.A. (IT) 1997-05-07 EP disclosed
EP-0758563-A1 OLEFIN OLIGOMERIZATION CATALYST AND PROCESS FOR THE PREPARATION OF OLEFIN OLIGOMER USING IT NIPPON OIL COMPANY, LTD. (JP) 1997-02-19 EP disclosed
US-4104314-A 1-CHLORO-2,2,2-TRIFLUOROETHYL 1,1,2,2-TETRAFLUOROETHYL ETHER, ANESTHETICS, SOLVENTS AND DISPERSANTS FOR FLUORINATED MATERIALS AIRCO, INC. (US) 1978-08-01 US disclosed
US-4059639-A 1,2,2,2-TETRAFLUOROETHYL-1',1',-DIFLUORO-2',2'-DICHLOROETHYL ETHER, ANESTHETIC AIRCO, INC. (US) 1977-11-22 US disclosed
US-3987111-A FLUORINATED ALIPHATIC ETHERS; ANESTHETICS AIRCO, INC. (US) 1976-10-19 US disclosed
US-3947595-A 2.2 Dichloro -1,1,-difluoroethyl-1,2,2,2- tetrofluoroethyl ether as an inhalation anesthetic AIRCO, INC. (US) 1976-03-30 US disclosed