SCHEMBL570480

SCHEMBL570480

COc1ccc(Cc2ccccc2)cc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
LTA4H P09960 4/20 1.00
SIGMAR1 Q99720 2/20 0.60
CA4 P22748 1/20 0.59
MEN1 O00255 1/20 0.57
KMT2A Q03164 1/20 0.57
CALM1 P0DP23 1/20 0.57
HTT P42858 1/20 0.56
IDO1 P14902 1/20 0.54
SAE1 Q9UBE0 1/20 0.53
UBA2 Q9UBT2 1/20 0.53
RAB9A P51151 2/20 0.53
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA7 P43166 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
NPC1 O15118 1/20 0.52
L3MBTL1 Q9Y468 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Nitrogen SCHEMBL28594721 0.96 LTA4H (0.91) LTA4HSIGMAR1CA4MEN1KMT2A
SCHEMBL5551078 0.94 LTA4H (0.88) LTA4HSIGMAR1CA4MEN1KMT2A
SCHEMBL27884 0.90 LTA4H (0.81) LTA4HIDO1SAE1UBA2CA12
SCHEMBL25986524 0.90 LTA4H (0.81) LTA4HIDO1SAE1UBA2CA12
SCHEMBL1425001 0.90 LTA4H (0.81) LTA4HIDO1SAE1UBA2CA12
SCHEMBL27666880 0.90 LTA4H (0.81) LTA4HSIGMAR1CA4MEN1KMT2A
SCHEMBL11819224 0.89 LTA4H (0.80) LTA4HSIGMAR1CA4KMT2ARAB9A
Sulfuric Acid SCHEMBL29799164 0.88 LTA4H (0.78) LTA4HSIGMAR1MEN1KMT2AHTT
SCHEMBL28875158 0.88 LTA4H (0.78) LTA4HSIGMAR1MEN1KMT2AHTT
Ammonia Solution, Strong SCHEMBL20919857 0.87 LTA4H (0.77) LTA4HIDO1SAE1UBA2CA12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 508 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117836304-A Improved oligonucleotide synthesis 巴克姆股份公司 2024-04-05 CN claimed
CN-114249786-A Preparation and application of nucleoside intermediate containing N, N-diacyl structure 上海彩迩文生化科技有限公司 2022-03-29 CN claimed
CN-113429307-A Preparation method and application of stable isotope labeled glutamic acid and glutamic acid derivative 深圳鼎邦生物科技有限公司 2021-09-24 CN claimed
CN-107790186-B Novel decamethyl cyclopentadienyl zirconium complex and preparation method and application thereof 山西医科大学 2020-10-30 CN claimed
CN-106565517-B A method of amide is prepared by arylmethane derivative and nitrile 湖南大学 2018-08-17 CN claimed
CN-106565517-A Method for preparing amide from aryl methane derivative and nitrile 湖南大学 2017-04-19 CN claimed
EP-2702041-A1 ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF Chiesi Farmaceutici S.p.A. (IT) 2014-03-05 EP claimed
US-8604015-B2 Alkaloid ester and carbamate derivatives and medicinal compositions thereof CHIESI FARMACEUTICI S.P.A. (IT) 2013-12-10 US claimed
US-8492384-B2 Imidazolylalkylcarbonyl derivatives as calcium channel modulators and preparation method thereof KOREA INSTITUTE OF SCIENCE AND TECHNOLOGY (KR) 2013-07-23 US claimed
US-20120276018-A1 ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF CHIESI FARMACEUTICI S.P.A. (IT) 2012-11-01 US claimed
US-4566996-A Process for preparing azetidinone derivatives Otsuke Kagaku Yakuhin Kabushiki Kaisha (JP) 1986-01-28 US claimed
US-4473713-A Hydrolysis of aryl-aliphatic ethers RHONE-POULENC SPECIALITES CHIMIQUES (FR) 1984-09-25 US claimed
US-4181733-A ANTIBIOTICS MERCK & CO., INC. (US) 1980-01-01 US claimed
US-4167630-A Process for epimerizing beta-lactam antibiotic compounds, and related products MERCK & CO., INC. (US) 1979-09-11 US claimed
US-4107432-A ANTIBIOTICS MERCK & CO., INC. (US) 1978-08-15 US claimed
US-4058661-A 7-Diacyl cephalosporins MERCK & CO., INC. (US) 1977-11-15 US claimed
US-4053286-A ACYLATION MERCK & CO., INC. (US) 1977-10-11 US claimed
US-4051132-A Process for epimerizing beta-lactam antibiotic compounds by means of an acid quench MERCK & CO., INC. (US) 1977-09-27 US claimed
US-4014873-A Process for the production of 7-acylamidocephalosporins MERCK & CO., INC. (US) 1977-03-29 US claimed
US-3932393-A 3-Methylenecephalosporins and process for production thereof ELI LILLY AND COMPANY (US) 1976-01-13 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120276018-A1 ALKALOID ESTER AND CARBAMATE DERIVATIVES AND MEDICINAL COMPOSITIONS THEREOF CHRM3, BCHE, CHRM1 LTA4H 324/4885SIGMAR1 1448/4885CA4 70/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.