Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | ESR1 | P03372 | 2/20 | 0.41 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.37 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.37 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.37 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.37 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.37 |
| ▸ | NOX1 | Q9Y5S8 | 1/20 | 0.35 |
| ▸ | IDO1 | P14902 | 2/20 | 0.33 |
| ▸ | TDO2 | P48775 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10340769 | 0.76 | TSHR (0.46) | TSHRCYP1A2ESR1ESR2LMNA | |
| SCHEMBL10523777 | 0.75 | ESR1 (0.58) | TSHRCYP1A2ESR1ESR2LMNA | |
| SCHEMBL10520597 | 0.75 | ESR1 (0.58) | TSHRCYP1A2ESR1ESR2LMNA | |
| SCHEMBL10522698 | 0.73 | CYP1A2 (0.52) | TSHRCYP1A2ESR1LMNACYP2A6 | |
| SCHEMBL2870880 | 0.73 | CYP1A2 (0.52) | TSHRCYP1A2ESR1LMNACYP2A6 | |
| SCHEMBL31333180 | 0.71 | ESR1 (0.44) | TSHRESR1ESR2GAAL3MBTL1 | |
| SCHEMBL28680131 | 0.70 | TSHR (0.47) | TSHRCYP1A2ESR1ESR2LMNA | |
| SCHEMBL10521146 | 0.70 | TSHR (0.43) | TSHRCYP1A2ESR1ESR2LMNA | |
| 1,4-Dichlorobenzene SCHEMBL9297848 | 0.69 | TSHR (0.92) | TSHRCYP1A2LMNACYP2A6CES2 | |
| SCHEMBL24715429 | 0.66 | TSHR (1.00) | TSHRCYP1A2LMNACYP2A6CES2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1449845-B1 | Asymmetric phosphinoselenoic chloride and method for producing the same | PRESIDENT OF GIFU UNIVERSITY (JP) | 2006-09-13 | — | — | EP | disclosed |
| US-7060855-B2 | Asymmetric phosphinoselenoic chloride and method for producing the same | GIFU UNIVERSITY (JP) | 2006-06-13 | — | — | US | disclosed |
| US-20040167356-A1 | Asymmetric phosphinoselenoic chloride and method for producing the same | GIFU UNIVERSITY | 2004-08-26 | — | — | US | disclosed |
| EP-1449845-A2 | Asymmetric phosphinoselenoic chloride and method for producing the same | President of Gifu University (JP) | 2004-08-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040167356-A1 | Asymmetric phosphinoselenoic chloride and method for producing the same | PHOSPHO1, AGPAT5, PLCB1 | TSHR 1599/4885CYP1A2 1664/4885ESR1 4245/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.