SCHEMBL2870880

SCHEMBL2870880

O=P(c1ccccc1)(c1ccc(Cl)cc1)c1ccc(Cl)cc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.52
LMNA P02545 3/20 0.50
TSHR P16473 1/20 0.48
CA2 P00918 1/20 0.44
CA4 P22748 1/20 0.44
CA5A P35218 1/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 2/20 0.44
ALOX12 P18054 2/20 0.44
KDM4E B2RXH2 2/20 0.44
MAPT P10636 2/20 0.44
NPSR1 Q6W5P4 2/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
CES2 O00748 1/20 0.43
CES1 P23141 1/20 0.43
PTGS2 P35354 1/20 0.42
ESR1 P03372 1/20 0.41
CYP2A6 P11509 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10522698 1.00 CYP1A2 (0.52) CYP1A2LMNATSHRCA2CA4
SCHEMBL1000520 0.89 LMNA (0.50) CYP1A2LMNATSHRCA2CA4
SCHEMBL10523794 0.88 TSHR (0.42) CYP1A2LMNATSHRALDH1A1HPGD
SCHEMBL5436616 0.87 LMNA (0.60) LMNATSHRCA2CA4CA5A
SCHEMBL132983 0.87 LMNA (0.60) LMNATSHRCA2CA4CA5A
SCHEMBL5439069 0.87 LMNA (0.60) LMNATSHRCA2CA4CA5A
Triphenylphosphine Oxide SCHEMBL3949 0.84 CA2 (0.58) LMNATSHRCA2CA4CA5A
Triphenylphosphine Oxide SCHEMBL513223 0.84 CA2 (0.58) LMNATSHRCA2CA4CA5A
SCHEMBL10524389 0.83 NPSR1 (0.40) CYP1A2LMNATSHRCA2CA4
SCHEMBL4774848 0.81 LMNA (0.56) LMNATSHRCA2CA4CA5A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118221725-A Additive of tin-lead mixed perovskite film, and preparation method and application thereof 正泰新能科技股份有限公司 2024-06-21 CN disclosed
US-11208533-B2 Flame-retardant and abrasion-resistant composite NICHING INDUSTRIAL CORP. (TW) 2021-12-28 US disclosed
US-20190352473-A1 FLAME-RETARDANT AND ABRASION-RESISTANT COMPOSITE NICHING INDUSTRIAL CORP. (TW) 2019-11-21 US disclosed
EP-3569650-A1 FLAME-RETARDANT AND ABRASION-RESISTANT COMPOSITE Niching Industrial Corp. (CN) 2019-11-20 EP disclosed
US-9722270-B2 Polymer, electrolyte membrane and electrode for a fuel cell, each including the polymer, fuel cell including at least one of the electrolyte membrane, and the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-01 US disclosed
US-9722270-B2 Polymer, electrolyte membrane and electrode for a fuel cell, each including the polymer, fuel cell including at least one of the electrolyte membrane, and the electrode SAMSUNG ELECTRONICS CO., LTD. (KR) 2017-08-01 US disclosed
US-20150037708-A1 POLYMER, ELECTROLYTE MEMBRANE AND ELECTRODE FOR A FUEL CELL, EACH INCLUDING THE POLYMER, FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTROLYTE MEMBRANE, AND THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-02-05 US disclosed
US-20150037708-A1 POLYMER, ELECTROLYTE MEMBRANE AND ELECTRODE FOR A FUEL CELL, EACH INCLUDING THE POLYMER, FUEL CELL INCLUDING AT LEAST ONE OF THE ELECTROLYTE MEMBRANE, AND THE ELECTRODE SAMSUNG ELECTRONICS CO., LTD. (KR) 2015-02-05 US disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-7635744-B2 Trifluorovinyloxy monomers and polymers GENERAL ELECTRIC COMPANY (US) 2009-12-22 US disclosed
US-5407528-A Protecting surface by applying polyphosphine oxide THE CENTER FOR INNOVATIVE TECHNOLOGY (US) 1995-04-18 US disclosed
US-4990588-A Temperature resistant aromatic polyethers ROHM GMBH (DE) 1991-02-05 US disclosed
US-4816605-A Process for the preparation of bifunctional tertiary aromatic phosphine oxides HOECHST AKTIENGESELLSCHAFT (DE) 1989-03-28 US disclosed
US-4806691-A Process for the preparation of tertiary phosphine oxides HOECHST AKTIENGESELLSCHAFT (DE) 1989-02-21 US disclosed
US-4760191-A Preparation of bis(4-halophenyl)phenylphosphine oxide AKZO AMERICA INC. (US) 1988-07-26 US disclosed
US-4745224-A Methods for making tertiary phosphine oxides ROHM GMBH (DE) 1988-05-17 US disclosed
US-4745225-A HEAT RESISTANCE, FIREPROOFING POLYMERS ROHM GMBH (DE) 1988-05-17 US disclosed
US-4696993-A POLYCONDENSATION OF CHLOROPHENYL PHOSPHINE OXIDES ROHM GMBH (DE) 1987-09-29 US disclosed
US-4675446-A OXIDATION OF PHOSPHINE SULFIDES HOECHST AKTIENGESELLSCHAFT (DE) 1987-06-23 US disclosed
US-4492805-A NONFLAMMABLE ENGINEERING THERMOPLASTICS ROHM GMBH (DE) 1985-01-08 US disclosed