Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 20/20 | 0.78 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5704913 | 0.99 | HTR6 (0.76) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL5704851 | 0.88 | HTR6 (1.00) | HTR6HTR1ADRD2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL5704752 | 0.87 | HTR6 (0.98) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL5704923 | 0.86 | HTR6 (0.81) | HTR6HTR1ADRD2HTR2AHTR7 | |
| SCHEMBL5704880 | 0.86 | HTR6 (0.81) | HTR6 | |
| SCHEMBL4306533 | 0.85 | HTR6 (1.00) | HTR6DRD2 | |
| Hydrochloric Acid SCHEMBL5704887 | 0.85 | HTR6 (0.79) | HTR6 | |
| Hydrochloric Acid SCHEMBL5705074 | 0.85 | HTR6 (0.79) | HTR6HTR1ADRD2HTR2AHTR7 | |
| Hydrochloric Acid SCHEMBL5704792 | 0.84 | HTR6 (0.98) | HTR6DRD2 | |
| SCHEMBL5704922 | 0.84 | HTR6 (0.92) | HTR6HTR1ADRD2HTR2AHTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335722-B1 | INDOLYL-SULFONYL- COMPOUNDS USEFUL IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2006-08-30 | — | — | EP | claimed |