Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.77 |
| ▸ | MET | P08581 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5704997 | 0.91 | HTR6 (0.66) | HTR6 | |
| SCHEMBL5704813 | 0.90 | HTR6 (0.71) | HTR6 | |
| Hydrochloric Acid SCHEMBL5704875 | 0.89 | HTR6 (0.69) | HTR6 | |
| SCHEMBL5704872 | 0.87 | HTR6 (1.00) | HTR6 | |
| Hydrochloric Acid SCHEMBL5704801 | 0.86 | HTR6 (0.98) | HTR6 | |
| SCHEMBL4306533 | 0.86 | HTR6 (1.00) | HTR6 | |
| Hydrochloric Acid SCHEMBL5704792 | 0.85 | HTR6 (0.98) | HTR6 | |
| SCHEMBL5704851 | 0.84 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5704782 | 0.83 | HTR6 (1.00) | HTR6 | |
| SCHEMBL5704810 | 0.83 | HTR6 (1.00) | HTR6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1335722-B1 | INDOLYL-SULFONYL- COMPOUNDS USEFUL IN THE TREATMENT OF CNS DISORDERS | SMITHKLINE BEECHAM PLC (GB) | 2006-08-30 | — | — | EP | claimed |