Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.74 |
| ▸ | GLA | P06280 | 1/20 | 0.74 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.61 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.61 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.61 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.61 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.61 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.61 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.61 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.61 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.61 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.61 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.61 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.61 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | RAB9A | P51151 | 3/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.55 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.51 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.51 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14215541 | 0.92 | GLA (0.74) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL580001 | 0.88 | GLA (0.72) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL15468096 | 0.87 | GLA (0.70) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL793743 | 0.87 | KMT2A (0.70) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL159762 | 0.87 | GLA (0.70) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL29339723 | 0.87 | KMT2A (0.70) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL159731 | 0.87 | GLA (0.70) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL158220 | 0.86 | HDAC3 (0.78) | KMT2AGLAHDAC3HDAC4HDAC1 | |
| SCHEMBL20961904 | 0.86 | KMT2A (0.59) | KMT2AGLANPC1RAB9ASMN1; SMN2 | |
| SCHEMBL793998 | 0.85 | GLA (1.00) | KMT2AGLAHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1255728-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | claimed |
| US-20030162995-A1 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES LLC | 2003-08-28 | — | — | US | claimed |
| EP-1255728-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | Enichem S.p.A. (IT) | 2002-11-13 | — | — | EP | claimed |
| WO-2001056977-A1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | ENICHEM S.P.A. (IT) | 2001-08-09 | — | — | WO | claimed |
| EP-1255728-B1 | INTEGRATED PROCESS FOR THE PREPARATION OF AROMATIC ISOCYANATES AND PROCEDURES FOR EFFECTING THE RELATIVE INTERMEDIATE PHASES | DOW GLOBAL TECHNOLOGIES INC (US) | 2006-08-30 | — | — | EP | disclosed |
| US-6992214-B2 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20030162995-A1 | Integrated process for the preparation of aromatic isocyanates and procedures for effecting the relative intermediate phases | DOW GLOBAL TECHNOLOGIES LLC | 2003-08-28 | — | — | US | disclosed |
| US-5457229-A | Reacting with chloro, bromo- or iodo-borane and tertiary amine in nonpolar solvent | UNIVERSITY OF OTTAWA (CA) | 1995-10-10 | — | — | US | disclosed |
| EP-0143320-B1 | METHOD FOR THE PREPARATION OF ISOCYANATES BY THERMAL DECOMPOSITION OF URETHANES | BASF Aktiengesellschaft (DE) | 1988-01-20 | — | — | EP | disclosed |
| EP-0078005-B1 | METHOD FOR THE PREPARATION OF ISOCYANATES BY PYROLYSIS OF URETHANES | BASF Aktiengesellschaft (DE) | 1985-08-07 | — | — | EP | disclosed |
| EP-0143320-A2 | Method for the preparation of isocyanates by thermal decomposition of urethanes | BASF Aktiengesellschaft (DE) | 1985-06-05 | — | — | EP | disclosed |
| EP-0028724-B1 | PROCESS FOR PREPARING ARYL ISOCYANATES BY THERMAL DECOMPOSITION OF ARYL URETHANES | BASF Aktiengesellschaft (DE) | 1984-09-12 | — | — | EP | disclosed |
| EP-0078005-A1 | Method for the preparation of isocyanates by pyrolysis of urethanes | BASF Aktiengesellschaft (DE) | 1983-05-04 | — | — | EP | disclosed |
| US-4330479-A | ZINC OR ALUMINUM CATALYST | BASF AKTIENGESELLSCHAFT (DE) | 1982-05-18 | — | — | US | disclosed |
| EP-0028724-A1 | Process for preparing aryl isocyanates by thermal decomposition of aryl urethanes | BASF Aktiengesellschaft (DE) | 1981-05-20 | — | — | EP | disclosed |