Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.72 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.62 |
| ▸ | F13A1 | P00488 | 1/20 | 0.62 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.59 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.59 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.59 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.59 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.59 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.59 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.59 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.59 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.59 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.59 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.59 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.51 |
| ▸ | ESRRG | P62508 | 4/20 | 0.50 |
| ▸ | ESRRB | O95718 | 3/20 | 0.50 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705148 | 0.88 | KMT2A (0.74) | GLAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL159762 | 0.85 | GLA (0.70) | GLAKMT2AKDM4EF13A1HDAC3 | |
| SCHEMBL793743 | 0.85 | KMT2A (0.70) | GLAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL15468096 | 0.85 | GLA (0.70) | GLAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL29339723 | 0.85 | KMT2A (0.70) | GLAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL159731 | 0.85 | GLA (0.70) | GLAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL158220 | 0.85 | HDAC3 (0.78) | GLAKMT2AHDAC3HDAC4HDAC1 | |
| SCHEMBL4769744 | 0.84 | KMT2A (0.57) | GLAKMT2AKDM4EF13A1HDAC3 | |
| SCHEMBL3700733 | 0.84 | KDM4E (0.68) | GLAKMT2AKDM4EF13A1ABCG2 | |
| SCHEMBL793998 | 0.84 | GLA (1.00) | GLAKMT2AKDM4EHDAC3HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9161542-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2015-10-20 | — | — | US | claimed |
| US-20120302611-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2012-11-29 | — | — | US | claimed |
| WO-2012162595-A2 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2012-11-29 | — | — | WO | claimed |
| US-9161542-B2 | Pesticidal compositions and related methods | DOW AGROSCIENCES LLC (US) | 2015-10-20 | — | — | US | disclosed |
| US-8338611-B2 | Opioid receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338611-B2 | Opioid receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-12-25 | — | — | US | disclosed |
| US-8338611-B2 | Opioid receptor antagonists | ELI LILLY AND COMPANY (US) | 2012-12-25 | — | — | US | disclosed |
| US-20120302611-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2012-11-29 | — | — | US | disclosed |
| WO-2012162595-A2 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | DOW AGROSCIENCES LLC (US) | 2012-11-29 | — | — | WO | disclosed |
| EP-1735268-B1 | OPIOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1735268-B1 | OPIOID RECEPTOR ANTAGONISTS | LILLY CO ELI (US) | 2012-02-15 | — | — | EP | disclosed |
| EP-1735268-A1 | OPIOID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2006-12-27 | — | — | EP | disclosed |
| US-20060217372-A1 | Diaryl ethers as opioid receptor antagonist | ELI LILLY AND COMPANY | 2006-09-28 | — | — | US | disclosed |
| CN-1681498-A | Diaryl ethers as opioid receptor antagonist | LILLY CO ELI (US) | 2005-10-12 | — | — | CN | disclosed |
| WO-2005092836-A1 | OPIOID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-10-06 | — | — | WO | disclosed |
| EP-1562595-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONISTS | ELI LILLY AND COMPANY (US) | 2005-08-17 | — | — | EP | disclosed |
| WO-2004026305-A1 | DIARYL ETHERS AS OPIOID RECEPTOR ANTAGONIST | ELI LILLY AND COMPANY (US) | 2004-04-01 | — | — | WO | disclosed |
| EP-0161484-B1 | ESSENTIALLY ORTHO-LINKED POLY(ARYL ETHERS) | BAYER AG (DE) | 1988-09-21 | — | — | EP | disclosed |
| US-4705843-A | Process for the production of substituted polyaryl ethers | BAYER AKTIENGESELLSCHAFT (DE) | 1987-11-10 | — | — | US | disclosed |
| EP-0161484-A1 | Essentially ortho-linked poly(aryl ethers) | BAYER AG (DE) | 1985-11-21 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120302611-A1 | PESTICIDAL COMPOSITIONS AND RELATED METHODS | PRDX6, PRDX2, PRDX1 | GLA 2694/4885KMT2A 1704/4885KDM4E 777/4885 |
| US-20060217372-A1 | Diaryl ethers as opioid receptor antagonist | OPRM1, OPRL1, OPRD1 | GLA 3319/4885KMT2A 2069/4885KDM4E 608/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.