SCHEMBL5705200

SCHEMBL5705200

C#CC(O)CCCCCCCC

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
GPR84 Q9NQS5 7/20 0.45
SPHK1 Q9NYA1 2/20 0.45
FFAR1 O14842 1/20 0.45
LMNA P02545 2/20 0.44
CYP2D6 P10635 2/20 0.42
GMNN O75496 1/20 0.42
POLB P06746 1/20 0.42
THPO P40225 1/20 0.42
MTOR P42345 1/20 0.42
BLM P54132 1/20 0.42
KDM4E B2RXH2 1/20 0.42
TP53 P04637 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP3A4 P08684 1/20 0.42
MAPT P10636 1/20 0.42
CETP P11597 1/20 0.42
HTT P42858 1/20 0.42
UBE2N P61088 1/20 0.42
HMGCR P04035 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5046213 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL12994143 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL1888013 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL1293252 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL996234 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL15283585 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL6285996 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL9793919 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL15283559 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6
SCHEMBL15283911 1.00 GPR84 (0.45) GPR84SPHK1FFAR1LMNACYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20060193880-A1 Method and compositions for attracting mosquitoes employing (R)-(+)-isomers of 1-alkyn-3-ols BEDOUKIAN RESEARCH, INC. 2006-08-31 US disclosed
EP-1695622-A2 Method and compositions for attracting mosquitoes employing (R)-(+)-isomers of 1-alkyn-3-ols Bedoukian Reseach Inc. (US) 2006-08-30 EP disclosed
EP-0339046-B1 LEUKOTRIENE B 4 ANALOGS UPJOHN CO (US) 1995-02-15 EP disclosed
EP-0319900-B1 FURYL, PHENYLENE AND THIENYL LEUKOTRIENE B4 ANALOGUES G.D. Searle & Co. (US) 1993-09-29 EP disclosed
US-5116981-A Antiinflammatory leukotriene B4 analogs THE UPJOHN COMPANY (US) 1992-05-26 US disclosed
US-4970229-A ANTIINFLAMMATORY AGENTS G. D. SEARLE & CO. (US) 1990-11-13 US disclosed
US-4970234-A ANTIINFLAMMATORY AGENTS G. D. SEARLE & CO. (US) 1990-11-13 US disclosed
EP-0339046-A1 LEUKOTRIENE B 4? ANALOGS. UPJOHN CO (US) 1989-11-02 EP disclosed
US-4855324-A ANTIINFLAMMATORY AGENTS G. D. SEARLE & CO. (US) 1989-08-08 US disclosed
EP-0319900-A2 Furyl, phenylene and thienyl leukotriene B4 analogues G.D. Searle & Co. (US) 1989-06-14 EP disclosed
WO-1988005045-A1 LEUKOTRIENE B4 ANALOGS THE UPJOHN COMPANY (US) 1988-07-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060193880-A1 Method and compositions for attracting mosquitoes employing (R)-(+)-isomers of 1-alkyn-3-ols C3AR1, C5AR1, ARRB1 GPR84 344/4885SPHK1 392/4885FFAR1 181/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.