SCHEMBL5705437

SCHEMBL5705437

CC(O)c1ncnc(Cl)c1I

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 1/20 0.32
ADK P55263 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3912272 0.82 CHEK1 (0.32) CHEK1
SCHEMBL5705503 0.82 CHEK1 (0.32) CHEK1
SCHEMBL5705514 0.80 CHEK1 (0.32) CHEK1
SCHEMBL8014580 0.79
SCHEMBL1663039 0.78 ALDH1A1 (0.30)
SCHEMBL1553684 0.76
SCHEMBL5705474 0.74 TSHR (0.31)
SCHEMBL1350019 0.72
SCHEMBL311909 0.72 ALDH1A1 (0.39)
SCHEMBL16815481 0.67 NOTUM (0.39) CHEK1ADK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1074546-B1 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES UBE INDUSTRIES (JP) 2006-09-06 EP disclosed
US-6521627-B1 Insecticidal, acaricidal, nematocidal and fungicidal activities UBE INDUSTRIES, LTD. (JP) 2003-02-18 US disclosed
EP-1074546-A1 5-IODO-4-PHENETHYLAMINOPYRIMIDINE DERIVATIVES, INTERMEDIATES THEREOF, PROCESS FOR PRODUCING THE SAME AND AGRICULTURAL/HORTICULTURAL PESTICIDES Ube Industries, Ltd. (JP) 2001-02-07 EP disclosed