Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.34 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6651569 | 0.87 | KMT2A (0.47) | HSP90AA1KMT2AMEN1MAPTKCNH2 | |
| SCHEMBL6648613 | 0.87 | KCNH2 (0.39) | HSP90AA1KMT2AMEN1MAPTKCNH2 | |
| SCHEMBL6652610 | 0.84 | HSP90B1 (0.38) | HSP90AA1KMT2AMEN1MAPTKCNH2 | |
| SCHEMBL6650314 | 0.81 | HSP90AA1 (0.36) | HSP90AA1KMT2AMEN1MAPTKCNH2 | |
| SCHEMBL6651515 | 0.78 | KMT2A (0.48) | HSP90AA1KMT2AMEN1MAPTHIF1A | |
| SCHEMBL6648269 | 0.76 | KMT2A (0.46) | KMT2AKCNH2HIF1ACYP2D6TSHR | |
| SCHEMBL6650163 | 0.73 | PSEN1 (0.38) | KMT2AMEN1MAPTKCNH2CYP2D6 | |
| SCHEMBL31713029 | 0.70 | TLR8 (0.50) | KMT2AKCNH2LMNAALDH1A1 | |
| SCHEMBL6651433 | 0.69 | KMT2A (0.43) | KMT2AMEN1MAPTTSHRCYP2C19 | |
| SCHEMBL6649429 | 0.68 | KCNH2 (0.41) | KCNH2HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1695704-A1 | Derivatives of aryl (or heteroaryl) azolylcarbinols for the treatment of fibromyalgia | LABORATORIOS DEL DR. ESTEVE, S.A. (ES) | 2006-08-30 | — | — | EP | claimed |