Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.36 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 2/20 | 0.36 |
| ▸ | PLAA | Q9Y263 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705441 | 0.87 | HSP90AA1 (0.36) | KMT2AALDH1A1KCNH2CYP2D6TSHR | |
| SCHEMBL6648613 | 0.87 | KCNH2 (0.39) | KMT2AALDH1A1KCNH2CYP2D6TSHR | |
| SCHEMBL6648269 | 0.86 | KMT2A (0.46) | KMT2AALDH1A1POLBKCNH2TLR8 | |
| SCHEMBL6652610 | 0.84 | HSP90B1 (0.38) | KMT2AALDH1A1KCNH2CYP2D6TSHR | |
| SCHEMBL6651433 | 0.81 | KMT2A (0.43) | KMT2AALDH1A1POLBTLR8TSHR | |
| SCHEMBL6650314 | 0.81 | HSP90AA1 (0.36) | KMT2AALDH1A1KCNH2CYP2D6TSHR | |
| SCHEMBL6651515 | 0.81 | KMT2A (0.48) | KMT2AALDH1A1POLBCYP2D6TSHR | |
| SCHEMBL5600154 | 0.81 | ALDH1A1 (0.48) | KMT2AALDH1A1POLBKCNH2TLR8 | |
| SCHEMBL6115119 | 0.77 | ALDH1A1 (0.69) | KMT2AALDH1A1POLBKCNH2TLR8 | |
| SCHEMBL9269515 | 0.76 | KMT2A (0.51) | KMT2AALDH1A1POLBTLR8MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1103243-B1 | UTILIZATION OF ARYL(OR HETEROARYL)AZOLYLCARBINOL DERIVATIVES FOR THE TREATMENT OF TROUBLES MEDIATED BY AN EXCESS OF SUBSTANCE P | ESTEVE LABOR DR (ES) | 2004-01-07 | — | — | EP | claimed |