Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | LDHA | P00338 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL3732974 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL873149 | 1.00 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6536657 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563457 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2301863 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6576985 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL12760876 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL904478 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1003571 | 0.95 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL25251920 | 0.94 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236397-B | Development of surface-treated magnesium hydroxide-containing material | OMYA国际股份公司 | 2023-03-21 | — | — | CN | claimed |
| CN-112236397-A | Development of surface-treated magnesium hydroxide-containing material | OMYA国际股份公司 | 2021-01-15 | — | — | CN | claimed |
| US-20200263356-A1 | SELECTIVELY DEPOLYMERIZING CELLULOSIC MATERIALS FOR USE AS THERMAL AND ACOUSTIC INSULATORS | DTE MATERIALS INCORPORATED | 2020-08-20 | — | — | US | claimed |
| EP-3684571-A1 | SELECTIVELY DEPOLYMERIZING CELLULOSIC MATERIALS FOR USE AS THERMAL AND ACOUSTIC INSULATORS | DTE Materials Incorporated (US) | 2020-07-29 | — | — | EP | claimed |
| US-8871058-B2 | Addition of endothermic fire retardants to provide near neutral pH pulp fiber webs | INTERNATIONAL PAPER COMPANY (US) | 2014-10-28 | — | — | US | claimed |
| US-8663427-B2 | Addition of endothermic fire retardants to provide near neutral pH pulp fiber webs | INTERNATIONAL PAPER COMPANY (US) | 2014-03-04 | — | — | US | claimed |
| US-20130264020-A1 | ADDITION OF ENDOTHERMIC FIRE RETARDANTS TO PROVIDE NEAR NEUTRAL pH PULP FIBER WEBS | INTERNATIONAL PAPER COMPANY | 2013-10-10 | — | — | US | claimed |
| US-8460513-B2 | — | — | 2013-06-11 | — | — | US | claimed |
| US-20120255695-A1 | Addition of Endothermic Fire Retardants to Provide Near Neutral pH Pulp Fiber webs | INTERNATIONAL PAPER COMPANY (US) | 2012-10-11 | — | — | US | claimed |
| WO-2012018746-A1 | ADDITION OF ENDOTHERMIC FIRE RETARDANTS TO PROVIDE NEAR NEUTRAL PH PULP FIBER WEBS | INTERNATIONAL PAPER COMPANY (US) | 2012-02-09 | — | — | WO | claimed |
| CN-1543434-A | Compositions and methods for treating cells and plants | 沃尔特・H・冉克斯 | 2004-11-03 | — | — | CN | claimed |
| EP-1412284-A2 | COMPOSITION FOR TREATING CELLS AND METHODS FOR QUALITATIVELY AND QUANTITATIVELY CUSTOMIZING THE FORMULATION THEREOF FOR A HEURISTICALLY DERIVED LIVING CELL NUTRIENT-COMPOSITION-ON-DEMAND | Runkis, Walter H. (US) | 2004-04-28 | — | — | EP | claimed |
| US-20030073580-A1 | Composition for treating cells and method for qualitatively and quantitatively customizing the formulation thereof | RUNKIS WALTER H (US) | 2003-04-17 | — | — | US | claimed |
| WO-2002100772-A2 | COMPOSITION AND METHOD FOR TREATING CELLS AND PLANTS | RUNKIS WALTER H (US) | 2002-12-19 | — | — | WO | claimed |
| US-5627303-A | ALDOL CONDENSATION OF ACETONE, CALCINED MAGNESIUM/ALUMINUM MIXED OXIDE CATALYST | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1997-05-06 | — | — | US | claimed |
| EP-0640387-A1 | Preparation of isophorone using a magnesium/aluminum mixed oxide catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| EP-0640388-A1 | Magnesium/aluminum mixed oxide catalysts and their use in the production of aminoethers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | claimed |
| US-20230332352-A1 | SELECTIVELY DEPOLYMERIZING CELLULOSIC MATERIALS FOR USE AS THERMAL AND ACOUSTIC INSULATORS | DTE MATERIALS INCORPORATED | 2023-10-19 | — | — | US | disclosed |
| EP-0640387-A1 | Preparation of isophorone using a magnesium/aluminum mixed oxide catalyst | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | disclosed |
| EP-0640388-A1 | Magnesium/aluminum mixed oxide catalysts and their use in the production of aminoethers | UNION CARBIDE CHEMICALS & PLASTICS TECHNOLOGY CORPORATION (US) | 1995-03-01 | — | — | EP | disclosed |