Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL1003571 | 1.00 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2301863 | 1.00 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6536657 | 1.00 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL904703 | 0.95 | — | — | |
| Bicarbonate SCHEMBL2304976 | 0.95 | — | — | |
| Bicarbonate SCHEMBL2432323 | 0.95 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL570556 | 0.95 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL81419 | 0.95 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2050659 | 0.95 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL3732974 | 0.95 | CA4 (0.42) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 201 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12421379-B2 | Polyethylene pipe | BASF SE (DE) | 2025-09-23 | — | — | US | claimed |
| US-12209174-B2 | Polypropylene composition | BASF SE (DE) | 2025-01-28 | — | — | US | claimed |
| US-20230407050-A1 | METHOD FOR STABILIZING AN ORGANIC MATERIAL USING A STABILIZER MIXTURE | BASF SE (DE) | 2023-12-21 | — | — | US | claimed |
| US-20230146472-A1 | POLYOLEFIN COMPOSITIONS | BASF SE (DE) | 2023-05-11 | — | — | US | claimed |
| EP-4110862-A1 | POLYOLEFIN COMPOSITIONS | BASF SE (DE) | 2023-01-04 | — | — | EP | claimed |
| US-20220056239-A1 | A POLYPROPYLENE COMPOSITION | BASF SE (DE) | 2022-02-24 | — | — | US | claimed |
| EP-3898809-A1 | A POLYPROPYLENE COMPOSITION | BASF SE (DE) | 2021-10-27 | — | — | EP | claimed |
| EP-3649189-B1 | A POLYETHYLENE PIPE | BASF SE (DE) | 2021-04-14 | — | — | EP | claimed |
| WO-2020126752-A1 | A POLYPROPYLENE COMPOSITION | BASF SE (DE) | 2020-06-25 | — | — | WO | claimed |
| US-20200157324-A1 | A POLYETHYLENE PIPE | BASF SE (DE) | 2020-05-21 | — | — | US | claimed |
| WO-2015055852-A2 | COMPOSITION | ADDIVANT SWITZERLAND GMBH (CH) | 2015-04-23 | — | — | WO | claimed |
| WO-2012078276-A1 | CONVERSION OF SYNGAS TO MIXED ALCOHOLS ON SUPPORTED CoMoSx CATALYSTS | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-06-14 | — | — | WO | claimed |
| CN-100365508-C | Photosensitive resin composition, photosensitive element, resist pattern and method for producing the same, and laminated substrate | HITACHI CHEMICAL CO LTD (JP) | 2008-01-30 | — | — | CN | claimed |
| US-7179853-B2 | Resin dispersion for cationic electrodeposition and cationic electrodeposition coating composition including the same | DPI CO., LTD. (KR) | 2007-02-20 | — | — | US | claimed |
| CN-1284046-C | Photosensitive resin composition, photosensitive element, resist pattern, method for producing resist pattern, and substrate having the resist pattern laminated thereon | HITACHI CHEMICAL CO LTD (JP) | 2006-11-08 | — | — | CN | claimed |
| US-20050107496-A1 | Resin dispersion for cationic electrodeposition and cationic electrodeposition coating composition including the same | NOROO PAINT & COATINGS CO., LTD. (KR) | 2005-05-19 | — | — | US | claimed |
| US-6743837-B2 | EPOXY-AMINE ADDITION RESIN; AMINE FUNCTIONAL ACRYLIC CATIONIC POLYMER; ESTERIFICATION PRODUCT OF STYRENE-ALLYLALCOHOL COPOLYMER AND FATTY ACID; BLOCKED POLYISOCYANATE CURING AGENT; MANGANESE PHOSPHATE-ACID REACTION PRODUCT | DIP CO. LTD. (KR) | 2004-06-01 | — | — | US | claimed |
| US-20030094382-A1 | Resin dispersion for cationic electrodeposition and cationic electrodeposition coating composition including the same | DPI CO., LTD. | 2003-05-22 | — | — | US | claimed |
| CN-1390318-A | Photosensitive resin composition, photosensitive element produced using the photosensitive resin composition, method for producing resist pattern, and laminated substrate of resist pattern | HITACHI CHEMICAL CO LTD (JP) | 2003-01-08 | — | — | CN | claimed |
| US-4529769-A | Blend containing hydrotalcite | PHILLIPS PETROLEUM COMPANY (US) | 1985-07-16 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12421379-B2 | Polyethylene pipe | PUF60, PWWP2B, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | CA4 2881/4885CA1 2286/4885FAHD1 4725/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.