Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.47 |
| ▸ | MTOR | P42345 | 4/20 | 0.43 |
| ▸ | CA1 | P00915 | 4/20 | 0.42 |
| ▸ | CA2 | P00918 | 4/20 | 0.42 |
| ▸ | CA7 | P43166 | 3/20 | 0.42 |
| ▸ | CA12 | O43570 | 3/20 | 0.42 |
| ▸ | CA9 | Q16790 | 3/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CNR1 | P21554 | 1/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | GOT1 | P17174 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5705945 | 0.85 | MEN1 (0.47) | MEN1KMT2AMCHR1CNR1EPHX2 | |
| SCHEMBL4119011 | 0.83 | MCHR1 (0.58) | MEN1KMT2AMCHR1MTORCNR1 | |
| SCHEMBL4119984 | 0.82 | MEN1 (0.51) | MEN1KMT2AMCHR1MTORCA1 | |
| SCHEMBL5705917 | 0.81 | CNR1 (0.57) | MEN1KMT2AMCHR1CNR1EPHX2 | |
| SCHEMBL4108817 | 0.79 | MEN1 (0.50) | MEN1KMT2AMCHR1MTORCNR1 | |
| SCHEMBL4118376 | 0.79 | MCHR1 (0.66) | MEN1KMT2AMCHR1MTORCA1 | |
| SCHEMBL4128393 | 0.79 | MEN1 (0.52) | MEN1KMT2AMCHR1MTORCNR1 | |
| SCHEMBL4116418 | 0.79 | MEN1 (0.52) | MEN1KMT2AMCHR1MTORCNR1 | |
| SCHEMBL4112186 | 0.79 | MEN1 (0.60) | MEN1KMT2AMCHR1MTORCA1 | |
| SCHEMBL4108824 | 0.77 | CCR3 (0.48) | MEN1KMT2AMCHR1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | claimed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | claimed |
| EP-1711175-A1 | DIUREA DERIVATIVES | Active Biotech AB (SE) | 2006-10-18 | — | — | EP | disclosed |
| WO-2005074919-A1 | DIUREA DERIVATIVES | ACTIVE BIOTECH AB (SE) | 2005-08-18 | — | — | WO | disclosed |