Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.37 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.37 |
| ▸ | CACNB2 | Q08289 | 1/20 | 0.37 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28053097 | 0.94 | FAAH (0.45) | TSHRFAAHTRPV1ABCG2CACNA2D1 | |
| Ammonia Solution, Strong SCHEMBL30533991 | 0.92 | FAAH (0.44) | TSHRFAAHTRPV1ABCG2CACNA2D1 | |
| Ammonia Solution, Strong SCHEMBL30534028 | 0.92 | FAAH (0.44) | TSHRFAAHTRPV1ABCG2CACNA2D1 | |
| SCHEMBL29374663 | 0.90 | FAAH (0.48) | TSHRFAAHTRPV1ABCG2CACNA2D1 | |
| SCHEMBL27807843 | 0.88 | FAAH (0.40) | TSHRFAAHTRPV1ABCG2CACNA2D1 | |
| SCHEMBL9724790 | 0.85 | TSHR (0.42) | TSHRALDH1A1SMN1; SMN2 | |
| SCHEMBL28894791 | 0.83 | TSHR (0.50) | TSHRALDH1A1ABCG2PTGS1PPARG | |
| SCHEMBL31411089 | 0.83 | TSHR (0.38) | TSHRALDH1A1ABCG2PTGS1PPARG | |
| SCHEMBL25181774 | 0.83 | TSHR (0.46) | TSHRALDH1A1FFAR1SMN1; SMN2 | |
| SCHEMBL25181794 | 0.83 | TSHR (0.46) | TSHRALDH1A1FFAR1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1115775-B1 | HIGH CLARITY POLYETHYLENE COMPOSITIONS | EASTMAN CHEM CO (US) | 2006-10-25 | — | — | EP | claimed |
| US-6130293-A | High clarity polyethylene compositions | EASTMAN CHEMICAL COMPANY (US) | 2000-10-10 | — | — | US | claimed |
| EP-1115775-B1 | HIGH CLARITY POLYETHYLENE COMPOSITIONS | EASTMAN CHEM CO (US) | 2006-10-25 | — | — | EP | disclosed |
| US-6130293-A | High clarity polyethylene compositions | EASTMAN CHEMICAL COMPANY (US) | 2000-10-10 | — | — | US | disclosed |