Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.41 |
| ▸ | ITGA4 | P13612 | 2/20 | 0.41 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.38 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.38 |
| ▸ | ITGAL | P20701 | 1/20 | 0.38 |
| ▸ | NLRP3 | Q96P20 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ACACB | O00763 | 4/20 | 0.36 |
| ▸ | YAP1 | P46937 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706160 | 0.93 | ITGB1 (0.48) | GAARAB9AITGB1ITGA4ITGB2 | |
| SCHEMBL5706009 | 0.91 | ITGB1 (0.45) | GAARAB9AITGB1ITGA4ITGB2 | |
| SCHEMBL4649444 | 0.87 | GAA (0.47) | GAARAB9AITGB1ITGA4ITGB2 | |
| SCHEMBL4649446 | 0.87 | GAA (0.47) | GAARAB9AITGB1ITGA4ITGB2 | |
| SCHEMBL5706008 | 0.81 | ITGB1 (0.48) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL5706072 | 0.81 | ITGB1 (0.45) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL4648600 | 0.80 | ITGB1 (0.52) | GAARAB9AITGB1ITGA4ITGB2 | |
| SCHEMBL4649378 | 0.80 | ITGB1 (0.52) | GAARAB9AITGB1ITGA4ITGB2 | |
| SCHEMBL4648806 | 0.77 | ITGB1 (0.49) | GAARAB9AITGB1ITGA4ITGB2 | |
| SCHEMBL4648805 | 0.77 | ITGB1 (0.49) | GAARAB9AITGB1ITGA4ITGB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701933-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005061440-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2005-07-07 | — | — | WO | disclosed |