Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 6/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 5/20 | 0.48 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.46 |
| ▸ | ICAM1 | P05362 | 1/20 | 0.46 |
| ▸ | ITGAL | P20701 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.39 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.38 |
| ▸ | ITGAV | P06756 | 1/20 | 0.38 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.38 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.38 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.37 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.37 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5706239 | 0.93 | GAA (0.45) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL5706008 | 0.88 | ITGB1 (0.48) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL5706072 | 0.88 | ITGB1 (0.45) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL5706009 | 0.87 | ITGB1 (0.45) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL4648600 | 0.87 | ITGB1 (0.52) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL4649378 | 0.87 | ITGB1 (0.52) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| Tetrahydrofuran SCHEMBL4648660 | 0.81 | ITGB1 (0.47) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL4649446 | 0.80 | GAA (0.47) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL4649444 | 0.80 | GAA (0.47) | ITGB1ITGA4ITGB2ICAM1ITGAL | |
| SCHEMBL4649064 | 0.79 | ITGA4 (0.59) | ITGB1ITGA4ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1701933-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005061440-A1 | NOVEL COMPOUNDS | TANABE SEIYAKU CO., LTD. (JP) | 2005-07-07 | — | — | WO | disclosed |