Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.68 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.68 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.68 |
| ▸ | TP53 | P04637 | 1/20 | 0.68 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.66 |
| ▸ | LMNA | P02545 | 5/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | POLB | P06746 | 1/20 | 0.58 |
| ▸ | ELANE | P08246 | 2/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10822266 | 0.97 | TSHR (0.71) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL4398193 | 0.93 | TSHR (0.71) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL5706189 | 0.92 | TSHR (0.63) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL7210188 | 0.90 | ALDH1A1 (0.64) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL5706042 | 0.90 | ALDH1A1 (0.64) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL1914270 | 0.90 | TSHR (0.60) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL5706195 | 0.89 | TSHR (0.59) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL1914077 | 0.89 | ALDH1A1 (0.61) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL1914044 | 0.89 | ALDH1A1 (0.61) | TSHRCYP3A4MAPK1TP53ALDH1A1 | |
| SCHEMBL1913805 | 0.89 | ALDH1A1 (0.61) | TSHRCYP3A4MAPK1TP53ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1412411-B1 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GEN ELECTRIC (US) | 2006-08-09 | — | — | EP | disclosed |
| EP-1412411-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2004-04-28 | — | — | EP | disclosed |
| US-6620902-B2 | Melting aromatic dihydroxy compound, a carbonic acid diester; mixing with endcapping agent under hermetic sealing | GENERAL ELECTRIC COMPANY | 2003-09-16 | — | — | US | disclosed |
| US-20030088051-A1 | Process for preparing polycarbonate and apparatus for preparing polycarbonate | GENERAL ELECTRIC COMPANY | 2003-05-08 | — | — | US | disclosed |
| WO-2003008481-A2 | PROCESS FOR PREPARING POLYCARBONATE AND APPARATUS FOR PREPARING POLYCARBONATE | GENERAL ELECTRIC COMPANY (US) | 2003-01-30 | — | — | WO | disclosed |