SCHEMBL5706405

SCHEMBL5706405

Cc1cc2sc[n+](CCCS(=O)(=O)O)c2cc1C

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ CYP2C19 P33261 1/20 0.35
▸ HSD17B10 Q99714 1/20 0.35
▸ ALDH1A1 P00352 3/20 0.33
▸ KDM4E B2RXH2 2/20 0.33
▸ HPGD P15428 3/20 0.33
▸ MAPT P10636 4/20 0.32
▸ L3MBTL1 Q9Y468 1/20 0.31
▸ THRB P10828 1/20 0.31
▸ RECQL P46063 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5685076 0.85 HPGD (0.38) ALDH1A1HPGDMAPTL3MBTL1
SCHEMBL9225469 0.83 HPGD (0.32) HPGDMAPT
SCHEMBL8641066 0.77 ALDH1A1 (0.46) ALDH1A1KDM4EHPGDMAPT
SCHEMBL9229131 0.74 SMN1; SMN2 (0.38) CYP2C19ALDH1A1HPGDMAPT
SCHEMBL9226423 0.73 MAPT (0.37) CYP2C19HSD17B10ALDH1A1KDM4EHPGD
Water SCHEMBL30750819 0.71 ALDH1A1 (0.44) ALDH1A1KDM4EHPGDMAPT
SCHEMBL9131663 0.71 HPGD (0.33) HPGDMAPT
SCHEMBL10747902 0.70 HSD17B10 (0.61) CYP2C19HSD17B10ALDH1A1KDM4EHPGD
SCHEMBL13043226 0.68 ALDH1A1 (0.33) ALDH1A1KDM4EMAPT
SCHEMBL5708457 0.63 KDM4E (0.58) ALDH1A1KDM4EMAPTRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0961165-B1 Direct x-ray elements capable of handling in ambient light EASTMAN KODAK CO (US) 2006-11-02 — — EP disclosed
US-6291153-B1 X-RAY FILM WITH SILVER HALIDE EMULSION HAVING BROMIDE WITH SOME IODIDE EASTMAN KODAK COMPANY 2001-09-18 — — US disclosed
EP-0961165-A1 Direct x-ray elements capable of handling in ambient light EASTMAN KODAK COMPANY (US) 1999-12-01 — — EP disclosed
US-5925505-A ELEMENT HAVING HYDROPHILIC COLLOID LAYER CONTAINING COMBINATION OF PROCESSING SOLUTION BLEACHABLE DYES TO REDUCE FOG UNDER ROOM LIGHT HANDLING CONDITIONS EASTMAN KODAK COMPANY (US) 1999-07-20 — — US disclosed
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