Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 5/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.39 |
| ▸ | RECQL | P46063 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | FYN | P06241 | 1/20 | 0.39 |
| ▸ | MMP2 | P08253 | 1/20 | 0.39 |
| ▸ | MMP9 | P14780 | 1/20 | 0.39 |
| ▸ | MMP8 | P22894 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
| ▸ | MMP12 | P39900 | 1/20 | 0.39 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL498541 | 0.85 | ALDH1A1 (0.40) | HPGDALOX15HSD17B10ALDH1A1TDP1 | |
| SCHEMBL9404581 | 0.77 | HPGD (0.47) | HPGDALOX15HSD17B10ALDH1A1TDP1 | |
| SCHEMBL9559685 | 0.71 | MEN1 (0.30) | MEN1KMT2A | |
| SCHEMBL5013871 | 0.70 | KDM4E (0.38) | HPGDALOX15HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5015297 | 0.70 | KDM4E (0.38) | HPGDALOX15HSD17B10ALDH1A1TDP1 | |
| SCHEMBL29453072 | 0.70 | ALDH1A1 (0.69) | HPGDALOX15HSD17B10ALDH1A1TDP1 | |
| SCHEMBL337585 | 0.70 | ALDH1A1 (0.69) | HPGDALOX15HSD17B10ALDH1A1TDP1 | |
| SCHEMBL3118129 | 0.69 | ALDH1A1 (0.46) | HPGDALOX15HSD17B10ALDH1A1TDP1 | |
| SCHEMBL5918765 | 0.69 | IDO1 (0.35) | IDO1 | |
| SCHEMBL8681981 | 0.68 | ALDH1A1 (0.58) | HPGDALOX15HSD17B10ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1699844-A1 | HYPERBRANCHED POLYMERS | THE UNIVERSITY OF SHEFFIELD (GB) | 2006-09-13 | — | — | EP | disclosed |
| WO-2005052023-A1 | HYPERBRANCHED POLYMERS | THE UNIVERSITY OF SHEFFIELD (GB) | 2005-06-09 | — | — | WO | disclosed |
| US-20050113554-A1 | Hyperbranched polymers | UNIVERSITY OF SHEFFIELD, THE (GB) | 2005-05-26 | — | — | US | disclosed |