Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.31 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.31 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | PDE4A | P27815 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29455702 | 0.89 | TSHR (0.43) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL22688963 | 0.89 | TSHR (0.43) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL10146952 | 0.77 | TSHR (0.41) | TSHRSLC1A3SLC1A2SLC1A1CYP2C9 | |
| SCHEMBL1143746 | 0.76 | TSHR (0.50) | TSHRCYP2C9PDE4ATP53 | |
| SCHEMBL9961488 | 0.76 | TSHR (0.50) | TSHRCYP2C9PDE4ATP53 | |
| SCHEMBL436408 | 0.76 | TSHR (0.50) | TSHRCYP2C9PDE4ATP53 | |
| SCHEMBL14296412 | 0.76 | TSHR (0.50) | TSHRCYP2C9PDE4ATP53 | |
| SCHEMBL21617331 | 0.75 | PDE4A (0.57) | TSHRCYP2C9PDE4A | |
| SCHEMBL21964008 | 0.75 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1 | |
| SCHEMBL76123 | 0.75 | TSHR (0.35) | TSHRSLC1A3SLC1A2SLC1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150337279-A1 | RECOMBINANT FUNGAL POLYPEPTIDES | SHELL OIL COMPANY | 2015-11-26 | — | — | US | disclosed |
| WO-2014081700-A1 | RECOMBINANT FUNGAL POLYPEPTIDES | CODEXIS, INC. (US) | 2014-05-30 | — | — | WO | disclosed |
| WO-2012078741-A2 | NOVEL FUNGAL ESTERASES | DYADIC INTERNATIONAL (USA) INC. (US) | 2012-06-14 | — | — | WO | disclosed |
| WO-2012018691-A2 | NOVEL FUNGAL ENZYMES | DYADIC INTERNATIONAL, INC. (US) | 2012-02-09 | — | — | WO | disclosed |