Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHBP | P24387 | 1/20 | 1.00 |
| ▸ | CRHR2 | Q13324 | 1/20 | 1.00 |
| ▸ | GPR35 | Q9HC97 | 3/20 | 0.57 |
| ▸ | CASP6 | P55212 | 1/20 | 0.53 |
| ▸ | ERN1 | O75460 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | GALK1 | P51570 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 1/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.47 |
| ▸ | CA2 | P00918 | 1/20 | 0.47 |
| ▸ | CA9 | Q16790 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trinitrophenol SCHEMBL27955220 | 0.89 | CRHBP (0.79) | CRHBPCRHR2GPR35CASP6ALDH1A1 | |
| SCHEMBL10885499 | 0.87 | CRHBP (0.76) | CRHBPCRHR2GPR35ERN1ALDH1A1 | |
| SCHEMBL3317242 | 0.87 | CRHBP (0.77) | CRHBPCRHR2GPR35CASP6ERN1 | |
| SCHEMBL6837874 | 0.84 | CRHBP (0.71) | CRHBPCRHR2ERN1ABCC1KCNMA1 | |
| SCHEMBL3559913 | 0.81 | CRHBP (0.68) | CRHBPCRHR2GPR35ALDH1A1TDP1 | |
| SCHEMBL5595131 | 0.81 | CRHBP (0.68) | CRHBPCRHR2GPR35ALDH1A1TDP1 | |
| SCHEMBL29878741 | 0.81 | CRHBP (0.68) | CRHBPCRHR2GPR35ALDH1A1TDP1 | |
| SCHEMBL29878908 | 0.81 | CRHBP (0.68) | CRHBPCRHR2GPR35ALDH1A1TDP1 | |
| SCHEMBL12818449 | 0.80 | CRHBP (0.67) | CRHBPCRHR2ALDH1A1TDP1ABCC1 | |
| SCHEMBL11672825 | 0.80 | CRHBP (0.67) | CRHBPCRHR2GPR35ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274673-B1 | METHOD FOR PRODUCING 4-HYDROXY-3-NITROBIPHENYL | SALTIGO GMBH (DE) | 2006-10-11 | — | — | EP | disclosed |
| US-6610893-B2 | Selectively nitrating 4-hydroxybiphenyl in the position adjacent to the phenolic hydroxyl group | BAYER AKTIENGESELLSCHAFT (DE) | 2003-08-26 | — | — | US | disclosed |