Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.31 |
| ▸ | SHBG | P04278 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28405594 | 0.95 | METAP1 (0.31) | METAP1 | |
| SCHEMBL21753853 | 0.93 | METAP1 (0.41) | METAP1EPHX1SHBGCYP1A2 | |
| SCHEMBL21753846 | 0.93 | METAP1 (0.37) | METAP1EPHX1SHBGCYP1A2 | |
| SCHEMBL4449485 | 0.93 | METAP1 (0.41) | METAP1EPHX1SHBGCYP1A2 | |
| SCHEMBL14931538 | 0.93 | METAP1 (0.41) | METAP1EPHX1SHBGCYP1A2 | |
| SCHEMBL9213385 | 0.75 | EPHX1 (0.33) | EPHX1SHBG | |
| SCHEMBL17416290 | 0.74 | — | — | |
| SCHEMBL5720721 | 0.73 | EPHX1 (0.37) | EPHX1SHBGCYP1A2 | |
| SCHEMBL9213591 | 0.73 | EPHX1 (0.37) | EPHX1SHBG | |
| SCHEMBL9213422 | 0.71 | EPHX1 (0.31) | EPHX1SHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1020439-B1 | CETP ACTIVITY INHIBITORS | JAPAN TOBACCO INC (JP) | 2006-08-30 | — | — | EP | disclosed |