Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.72 |
| ▸ | MAOB | P27338 | 8/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.51 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.51 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.51 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.51 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.51 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.51 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.51 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.51 |
| ▸ | ACHE | P22303 | 1/20 | 0.46 |
| ▸ | KIT | P10721 | 1/20 | 0.46 |
| ▸ | PNLIP | P16233 | 1/20 | 0.44 |
| ▸ | STK17B | O94768 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5707806 | 0.86 | ABCG2 (0.77) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707740 | 0.85 | ABCG2 (0.76) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707776 | 0.85 | ABCG2 (0.75) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707781 | 0.85 | ABCG2 (0.75) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| 4,6,3',4'-Tetramethoxyaurone SCHEMBL30804715 | 0.84 | ABCG2 (1.00) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707789 | 0.83 | ABCG2 (0.72) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707783 | 0.83 | ABCG2 (0.72) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707834 | 0.82 | ABCG2 (0.71) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707767 | 0.82 | ABCG2 (0.71) | ABCG2MAOBHDAC3HDAC4HDAC1 | |
| SCHEMBL5707778 | 0.82 | ABCG2 (0.71) | ABCG2MAOBHDAC3HDAC4HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20060228313-A1 | Method of cosmetic depigmentation care by applying at least one aurone | COLETICA (FR) | 2006-10-12 | — | — | US | claimed |
| EP-1709964-A2 | A method of cosmetic depigmentation care by applying at least one aurone | ENGELHARD LYON (FR) | 2006-10-11 | — | — | EP | claimed |
| US-20060228313-A1 | Method of cosmetic depigmentation care by applying at least one aurone | COLETICA (FR) | 2006-10-12 | — | — | US | disclosed |
| EP-1709964-A2 | A method of cosmetic depigmentation care by applying at least one aurone | ENGELHARD LYON (FR) | 2006-10-11 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060228313-A1 | Method of cosmetic depigmentation care by applying at least one aurone | TYR, MITF, MC1R | ABCG2 1836/4885MAOB 27/4885HDAC3 351/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.